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Dobutamine magnetic resonance imaging with myocardial tagging quantitatively predicts improvement in regional function after revascularization

1998; Elsevier BV; Volume: 82; Issue: 9 Linguagem: Inglês

10.1016/s0002-9149(98)00579-7

1879-1913

Dany Sayad, DuWayne L. Willett, W. Gregory Hundley, Paul Grayburn, Ronald M. Peshock,

Cardiac Structural Anomalies and Repair

Left ventricular dysfunction with heart failure carries a poor prognosis. 1 Kloner R.A Przyklenk K Hibernating and stunning of the myocardium. N Engl J Med. 1991; 325: 1877-1879 Crossref PubMed Scopus (58) Google Scholar Dobutamine stress echocardiography (DSE) has been shown to predict recovery of myocardial function after revascularization. 2 Cigarroa C.G deFilippi C.R Brickner M.E Alvarez L.G Wait M.A Grayburn P.A Dobutamine stress echocardiography identifies hibernating myocardium and predicts recovery of left ventricular function after coronary revascularization. Circulation. 1993; 88: 430-436 Crossref PubMed Scopus (467) Google Scholar , 3 La Canna G Alfieri O Giubbini R Gargano M Ferrari R Visioli O Echocardiography during infusion of dobutamine for identification of reversible dysfunction in patients with coronary artery disease. J Am Coll Cardiol. 1994; 23: 617-626 Abstract Full Text PDF PubMed Scopus (349) Google Scholar However, DSE relies on a semiquantitative assessment of function, requires adequate acoustic windows, and is limited by potential wall dropout in apical views. Further, because of the movement of the base toward the apex during ventricular contraction, systole and diastole are not properly superimposed, complicating the interpretation of wall thickening. We recently described a simple, highly reproducible magnetic resonance imaging (MRI) technique with myocardial tagging for the quantitative assessment of wall thickening. 4 Sayad D.E Willett D.L Bridges W.L McColl R Payne Chwialkowski M.H Peshock R.M Non-invasive quantitation of left ventricular wall thickening using cine MRI with myocardial tagging. Am J Cardiol. 1995; 76: 985-989 Abstract Full Text PDF PubMed Scopus (27) Google Scholar Three imaging planes are used similar to the apical views in echocardiography. The aim of this present study was to determine if the use of this new approach with dobutamine quantitatively predicts segmental recovery of myocardial function after revascularization.