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Fetal trisomy 10 mosaicism: ultrasound, cytogenetic and morphologic findings in early pregnancy

1999; Wiley; Volume: 19; Issue: 4 Linguagem: Inglês

10.1002/(sici)1097-0223(199904)19

1097-0223

Hans Knoblauch, D. Sommer, Claus Zimmer, C. Tennstedt, K. S. Heling, R Bollmann, Christiane Bommer, Sigrid Tinschert, H. Körner,

Tumors and Oncological Cases

Prenatal DiagnosisVolume 19, Issue 4 p. 379-382 Short Communication Fetal trisomy 10 mosaicism: ultrasound, cytogenetic and morphologic findings in early pregnancy H. Knoblauch, Corresponding Author H. Knoblauch Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanyInstitut für Medizinische Genetik, Universitätsklinikum Charité, Humboldt Universität, Luisenstr. 13, 10098 Berlin, Germany.Search for more papers by this authorD. Sommer, D. Sommer Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorC. Zimmer, C. Zimmer Institut für Pathologie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorC. Tennstedt, C. Tennstedt Institut für Pathologie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorK. Heling, K. Heling Zentrum für Pränatale Diagnostik und Therapie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorR. Bollmann, R. Bollmann Zentrum für Pränatale Diagnostik und Therapie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorC. Bommer, C. Bommer Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorS. Tinschert, S. Tinschert Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorH. Körner, H. Körner Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this author H. Knoblauch, Corresponding Author H. Knoblauch Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanyInstitut für Medizinische Genetik, Universitätsklinikum Charité, Humboldt Universität, Luisenstr. 13, 10098 Berlin, Germany.Search for more papers by this authorD. Sommer, D. Sommer Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorC. Zimmer, C. Zimmer Institut für Pathologie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorC. Tennstedt, C. Tennstedt Institut für Pathologie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorK. Heling, K. Heling Zentrum für Pränatale Diagnostik und Therapie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorR. Bollmann, R. Bollmann Zentrum für Pränatale Diagnostik und Therapie, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorC. Bommer, C. Bommer Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorS. Tinschert, S. Tinschert Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this authorH. Körner, H. Körner Institut für Medizinische Genetik, Universitätsklinikum Charité, Berlin, GermanySearch for more papers by this author First published: 26 April 1999 https://doi.org/10.1002/(SICI)1097-0223(199904)19:4 3.0.CO;2-TCitations: 14AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract We report the ultrasound, cytogenetic and morphologic findings in a case of trisomy 10 mosaicism prenatally detected by chorionic villus sampling (CVS). CVS sampling was carried out at the 13th week of gestation because of ultrasound diagnosis of hydrops fetalis and hygroma colli. Trisomy 10 mosaicism was diagnosed in cells from the cytotrophoblast (short-term culture) and the chorionic villus core (long-term culture). Fetal mosaicism was confirmed after termination of pregnancy in umbilical cord cells, placenta and fetal skin fibroblasts. Copyright © 1999 John Wiley & Sons, Ltd. REFERENCES De France HF, Beemer FA, Senders RC, Schaminée-Main SC. 1985. Trisomy 10 mosaicism in a newborn boy; delineation of the syndrome. Clin Genet 27: 92–96.Medline 10.1111/j.1399-0004.1985.tb00190.x CASPubMedWeb of Science®Google Scholar Farell SA, Sue-Chue-Lam A, Miskin M, Yao-Shan F. 1994. 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