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Primary Hyperparathyroidism Presenting as Fever of Unknown Origin with Unremitting Headache

1979; American College of Physicians; Volume: 91; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-91-4-575

1539-3704

Donald C. Blair, F. Robert Fekety,

Bone and Joint Diseases

Brief Reports1 October 1979Primary Hyperparathyroidism Presenting as Fever of Unknown Origin with Unremitting HeadacheDONALD C. BLAIR, M.D., F. ROBERT FEKETY JR., M.D.DONALD C. BLAIR, M.D.Search for more papers by this author, F. ROBERT FEKETY JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-91-4-575 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHyperparathyroidism, classically characterized by hypercalcemia, bone demineralization, and nephrolithiasis, is increasingly associated with more protean manifestations (1). We describe a patient with a parathyroid adenoma who presented with fever and intractable headache persisting for over a year before hyperparathyroidism was diagnosed. Headache as a major manifestation of hyperparathyroidism is rare, and, to our knowledge, presentation of the disease as fever of unknown origin has not been reported previously (1-4).A 29-year-old white woman presented to the clinic of the University of Michigan Medical Center in March 1972 with bilateral, dull, nonpulsatile temporal and frontal headaches dating from an upper respiratory...References1. AURBACHMALLETTEPATTENHEATHDOPPMANBILEZIKIAN GLBDJJ. Hyperparathyroidism: recent studies. Ann Intern Med. 1973;79:566-81. LinkGoogle Scholar2. PETERSDORFBEESON RP. Fever of unexplained origin: report on 100 cases. Medicine (Baltimore). 1961;40:1-30. CrossrefMedlineGoogle Scholar3. JACOBYSWARTZ GM. Fever of undetermined origin. N Engl J Med. 1973;289:1407-10. CrossrefMedlineGoogle Scholar4. SIMONDANIELS HG. Hormonal hyperthermia: endocrinologic causes of fever. Am J Med. 1979;66:257-63. CrossrefMedlineGoogle Scholar5. ARNAUDTSAOLITTLEDIKE CHT. Radioimmunoassay of human parathyroid hormone in serum. J Clin Invest. 1971;50:21-34. CrossrefMedlineGoogle Scholar6. HAWKER C. Parathyroid hormone: radioimmunoassay and clinical interpretation. Ann Clin Lab Sci. 1975;5:383-98. MedlineGoogle Scholar7. ALBRIGHTAUBBAUER FJW. Hyperparathyroidism: a common and polymorphic condition as illustrated by 17 proved cases from one clinic. JAMA. 1934;102:1276-87. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByMusculoskeletal manifestations of primary hyperparathyroidismAReferencesSevere neurological disease associated with hyperparathyroidismCase 21-1981 1 October 1979Volume 91, Issue 4Page: 575-576KeywordsBoneFever of unknown originFeversHeadachesHypercalcemiaHyperparathyroidismParathyroid tumors Issue Published: 1 October 1979 PDF DownloadLoading ...