Artigo Acesso aberto Revisado por pares

Association Between Variants in or Near PNPLA3, GCKR, and PPP1R3B With Ultrasound-Defined Steatosis Based on Data From the Third National Health and Nutrition Examination Survey

2013; Elsevier BV; Volume: 11; Issue: 9 Linguagem: Inglês

10.1016/j.cgh.2013.02.011

ISSN

1542-7714

Autores

Rubén Hernáez, Jody McLean, Mariana Lazo, Frederick L. Brancati, Joel N. Hirschhorn, Ingrid B. Borecki, Tamara B. Harris, Thutrang Nguyen, Ihab R. Kamel, Susanne Bonekamp, Mark S. Eberhardt, Jeanne M. Clark, Wen Hong Linda Kao, Elizabeth K. Speliotes,

Tópico(s)

Birth, Development, and Health

Resumo

A genome-wide association study associated 5 genetic variants with hepatic steatosis (identified by computerized tomography) in individuals of European ancestry. We investigated whether these variants were associated with measures of hepatic steatosis (HS) in non-Hispanic white (NHW), non-Hispanic black, and Mexican American (MA) participants in the US population-based National Health and Nutrition Examination Survey III, phase 2.

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