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Sequential cancer mutations in cultured human intestinal stem cells

2015; Nature Portfolio; Volume: 521; Issue: 7550 Linguagem: Inglês

10.1038/nature14415

1476-4687

Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen, Cheryl Zimberlin, Ruben van Boxtel, Arjan Buijs, Norman Sachs, René Overmeer, G. Johan A. Offerhaus, Harry Begthel, Jeroen Korving, Marc van de Wetering, Gerald Schwank, Meike E. W. Logtenberg, Edwin Cuppen, Hugo J.G. Snippert, Jan Paul Medema, Geert J.P.L. Kops, Hans Clevers,

CRISPR and Genetic Engineering