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Simple and an efficient method for the synthesis of 1-[2-dimethylamino-1-(4-methoxy-phenyl)-ethyl]-cyclohexanol hydrochloride: (±) venlafaxine racemic mixtures

2004; Elsevier BV; Volume: 14; Issue: 12 Linguagem: Inglês

10.1016/j.bmcl.2004.03.098

1464-3405

Basappa Basappa, C. V. Kavitha, Kanchugarakoppal S. Rangappa,

Chemical Reactions and Mechanisms

A novel synthetic method was developed for the synthesis of venlafaxine using inexpensive reagents. An improvement in the method, in the yield was achieved for the conversion of the venlafaxine. This is an improved version, simple and efficient method for the large-scale synthesis of venlafaxine.