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EFFECTS OF DIABETES ON FEMALE VOIDING BEHAVIOR

2004; Lippincott Williams & Wilkins; Volume: 172; Issue: 3 Linguagem: Inglês

10.1097/01.ju.0000136255.83054.0c

1527-3792

Wei‐Chia Lee, Huey-Peir Wu, Tong‐Yuan Tai, Shih‐Ping Liu, Jun Chen, Hong‐Jeng Yu,

Urinary Tract Infections Management

No AccessJournal of UrologyAdult Urology: Voiding Dysfunction1 Sep 2004EFFECTS OF DIABETES ON FEMALE VOIDING BEHAVIOR WEI-CHIA LEE, HUEY-PEIR WU, TONG-YUAN TAI, SHIH-PING LIU, JUN CHEN, and HONG-JENG YU WEI-CHIA LEEWEI-CHIA LEE More articles by this author , HUEY-PEIR WUHUEY-PEIR WU More articles by this author , TONG-YUAN TAITONG-YUAN TAI More articles by this author , SHIH-PING LIUSHIH-PING LIU More articles by this author , JUN CHENJUN CHEN More articles by this author , and HONG-JENG YUHONG-JENG YU More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000136255.83054.0cAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We studied voiding behavior in women with type 2 diabetes vs nondiabetic female controls and examined factors associated with voiding dysfunction in patients with diabetes. Materials and Methods: After eliminating coexisting medical factors that could affect voiding function we evaluated voiding behaviors in 194 female patients with diabetes treated regularly at a diabetic clinic and 162 control women using a lower urinary tract symptom questionnaire based mainly on the American Urological Association Symptom Index questionnaire and free flow analyses with post-void residual urine estimates. Emptying efficiency was defined as 100% × volume voided/(volume voided + post-void residual urine). Results: Compared with controls patients with diabetes had significantly higher nocturia scores (p = 0.003), weaker urinary streams (p = 0.02), less voided volumes (220 ± 97 vs 280 ± 104 ml, p = 0.04) and lower maximal flow rates (19.4 ± 8.4 vs 25.9 ± 8.5 ml per second, p <0.001). Remarkable residual urine (100 ml or greater) was detected in 1.8% of controls vs 13.9% of patients. After controlling for age and voided volume diabetes was significantly associated with a decrease in baseline maximum flow of 4.5 ml per second (95% CI 2.9 to 6.2). In patients with diabetes peripheral neuropathy was an independent factor associated with the decrease in emptying efficiency (p = 0.03). Conclusions: Diabetes significantly altered voiding patterns in a significant proportion of women treated at the diabetic clinic. Peripheral neuropathy is an important factor associated with diabetic voiding dysfunction. References 1 : Diabetic cystopathy: epidemiology and related disorders. Ann Intern Med1980; 92: 318. Google Scholar 2 : Diabetic cystopathy: relationship to autonomic neuropathy detected by sympathetic skin response. J Urol1997; 157: 580. Link, Google Scholar 3 : Urodynamic findings in patients with diabetic cystopathy. J Urol1995; 153: 342. Link, Google Scholar 4 : Effect of diabetes on lower urinary tract symptoms in patients with benign prostatic hyperplasia. 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Google Scholar From the Departments of Urology and Internal Medicine, College of Medicine, National Taiwan University and Taipei Municipal Hoping Hospital (W-CL), Taipei, Taiwan© 2004 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byLee W, Wu H, Tai T, Yu H and Chiang P (2018) Investigation of Urodynamic Characteristics and Bladder Sensory Function in the Early Stages of Diabetic Bladder Dysfunction in Women With Type 2 DiabetesJournal of Urology, VOL. 181, NO. 1, (198-203), Online publication date: 1-Jan-2009.Brown J (2018) Diabetic Cystopathy—What Does it Mean?Journal of Urology, VOL. 181, NO. 1, (13-14), Online publication date: 1-Jan-2009.Lee W, Chien C, Yu H and Lee S (2018) Bladder Dysfunction in Rats With Metabolic Syndrome Induced by Long-Term Fructose FeedingJournal of Urology, VOL. 179, NO. 6, (2470-2476), Online publication date: 1-Jun-2008. Volume 172Issue 3September 2004Page: 989-992 Advertisement Copyright & Permissions© 2004 by American Urological Association, Inc.Keywordsurinationurinary tractdiabetes mellitus, type 2diabetic neuropathiesurodynamicsMetricsAuthor Information WEI-CHIA LEE More articles by this author HUEY-PEIR WU More articles by this author TONG-YUAN TAI More articles by this author SHIH-PING LIU More articles by this author JUN CHEN More articles by this author HONG-JENG YU More articles by this author Expand All Advertisement PDF downloadLoading ...