Portal de Periódicos da CAPES

Testosterone, Growth Hormone and IGF-I Responses to Acute and Chronic Resistive Exercise in Men Aged 55-70 Years

1995; Thieme Medical Publishers (Germany); Volume: 16; Issue: 07 Linguagem: Inglês

10.1055/s-2007-973035

1439-3964

Barbara J. Nicklas, Anthony J. Ryan, M. Treuth, S. Mitchell Harman, Marcia A. Blackman, B. F. Hurley, M. A. Rogers,

Cardiovascular and exercise physiology

We investigated the responses of serum testosterone (T) and human growth hormone (hGH) concentrations to a bout of heavy resistive exercise and the responses of T, hGH, and insulinlike growth factor I (IGF-I) to a 16 wk progressive resistive training program in 13 men (60 ± 4 yrs). Body composition via hydrostatic weighing and muscle strength using a 3 repetition maximum (3RM) test on 6 variable resistance exercise machines were assessed before and after the training program. Fasting blood samples were drawn on 2 consecutive days prior to training and again on 2 consecutive days after the last day of exercise. Blood was also drawn immediately before and ~ 10 min after a single exercise session during the first wk of training, and after an exercise session of the same relative resistance during the last wk of training. The training program resulted in a 37 % increase in upper body strength and a 39 % increase in lower body strength (both p < 0.01). Lean body mass increased significantly (61.8 ± 2.1 vs 63.7 ± 7.8 kg; p < 0.001) while % fat decreased (26.5 ± 1.5 vs 24.9 ± 6.0 %; p < 0.01) as a result of training. Serum T concentration was unchanged, but GH increased ~ 18-fold in response to a single bout of resistive exercise before (0.24 ± 0.08 vs 4.60 ± 1.35 mg/l) and after (0.26 ± 0.06 vs 4.66 ± 1.46 mg/l; p < 0.01) training. Baseline serum concentrations of T, hGH, and IGF-I were unaffected by the training program. We conclude that an acute bout of resistive exercise causes a substantial hGH response in older men, but 16 wks of progressive resistive training does not affect baseline concentrations of the anabolic hormones.