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Artigo Revisado por pares
BIBTEX RIS

Synthesis by Escherichia coli of an abnormal β-galactosidase in the presence of thiouracil

1961; Elsevier BV; Volume: 3; Issue: 2 Linguagem: Inglês

10.1016/s0022-2836(61)80043-0

ISSN

1089-8638

Autores

R. Hamers, C. Hamers‐Casterman,

Tópico(s)

Enzyme Structure and Function

Resumo

In the presence of 2-thiouracil, the increase in β-galactosidase activity is inhibited to a greater extent than the corresponding protein assayed immunologically. It seems that the protein synthesized in the presence of the analogue loses some of its enzymic sites. It is suggested that this is a consequence of thiouracil incorporation into RNA templates or eventually into S-RNA.

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