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Lymphocytes as Models for the Study of Mammalian Cellular Differentiation

1977; Wiley; Volume: 33; Issue: 1 Linguagem: Inglês

10.1111/j.1600-065x.1977.tb00364.x

1600-065X

Harvey Cantor, Edward A. Boyse,

Monoclonal and Polyclonal Antibodies Research

Immunological ReviewsVolume 33, Issue 1 p. 105-124 Lymphocytes as Models for the Study of Mammalian Cellular Differentiation H. Cantor, H. Cantor Department of Medicine, Farber Cancer Center, Harvard Medical School, Boston, MA 02115 and Memorial Sloan-Kettering Cancer Center, New York, NY, 10021 USA. Supported by NIH Grants AI-12184, AI-13600, CA-08748 and CA-16889. Scholar of the Leukemia Society of America.Search for more papers by this authorE. A. Boyse, E. A. Boyse Department of Medicine, Farber Cancer Center, Harvard Medical School, Boston, MA 02115 and Memorial Sloan-Kettering Cancer Center, New York, NY, 10021 USA. Supported by NIH Grants AI-12184, AI-13600, CA-08748 and CA-16889.Search for more papers by this author H. Cantor, H. Cantor Department of Medicine, Farber Cancer Center, Harvard Medical School, Boston, MA 02115 and Memorial Sloan-Kettering Cancer Center, New York, NY, 10021 USA. Supported by NIH Grants AI-12184, AI-13600, CA-08748 and CA-16889. Scholar of the Leukemia Society of America.Search for more papers by this authorE. A. Boyse, E. A. Boyse Department of Medicine, Farber Cancer Center, Harvard Medical School, Boston, MA 02115 and Memorial Sloan-Kettering Cancer Center, New York, NY, 10021 USA. Supported by NIH Grants AI-12184, AI-13600, CA-08748 and CA-16889.Search for more papers by this author First published: January 1977 https://doi.org/10.1111/j.1600-065X.1977.tb00364.xCitations: 174 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Adamson, J. W., Fialkow, P. J., Murphy, S., Perchal, J.F. & Steinman, L. (1976) Polycythemia vera: Stem cell and probable clonal origin of the disease. N. Eng. J. Med. 295, 913. Amsbaugh, D. F., Hansen, C. T., Prescott, B., Stashak, P. W., Barthold, D. R. & Baker, P. J. (1972) Genetic control of the antibody response to type iii pneumococcal polysaccharide in mice. i. Evidence that an X-linked gene plays a decisive role in determining responsiveness. J. Exp. Med. 136, 931. Baltimore, D., Silverstone, A. E., Kung, P. C. Harrison, T. A. & McCaffrey, R. P. (1976) What cells contain terminal transferase? in: The Generation of Antibody Diversity: A New Look, ed. A. Cunningham, Academic Press, New York . (in press). Baumal, R. & Scharff, M. D. (1973) Synthesis assembly and secretion of mouse immunoglobulin. Transplant. Rev. 14, 163. Beverley, P. C. L., Woody, J., Dunkley, M. & Feldmann, M. (1976) Separation of suppressor and killer T cells by surface phenotype. Nature. (in press). Binz, H. & Wigzell, H. (1976) Antigen-binding idiotypic receptors from T cells. Analysis of their biochemistry, genetics and use as immunogens to produce specific immune tolerance. in: Origins of Lymphocyte Diversity-XLi. Cold Spring Harbor Symposium on Quantitative Biology (Cold Spring Harbor Laboratory of Quantitative Bid., Pub., New York ). (in press). Blomgren, H. & Andersson, B. (1970) Characteristics of the immunocompetent cells in the mouse thymus. Cell population changes during cortisone-induced atrophy and subsequent regeneration.. Cell immunol. 1, 545. Bortin, M. M., Rimm, A. A. & Saltzstein, E. C. (1969) Ontogenesis of immune capability of bone marrow cells and spleen cells against transplantation antigens. J. immunol. 105, 683. Boyse, E.A., Itakura, K., Stockert, E., Lritani, C.A. & Miura, M. (1971) Ly-C: A third locus specifying alloantigens expressed only on thymocytes and lymphocytes. Transplantation 11, 351. Boyse, E. A., Miyazawa, M., Aoki, T. & Old, L. J. (1968) Ly-A and Ly-B. Two systems of lymphocyte isoantigens in the mouse. Proc. Roy. Soc. B. 170, 175. Boyse, E. A. & Old, L. J. (1969) Some aspects of normal and abnormal cell surface genetics. Annu. Rev. Genet. 3, 269. Cantor, H. (1972) Two stages in lymphocyte development. Proc. 3rd LePetit Colloquium, London, Cell interactions 172 (North Holland, Amsterdam). Cantor, H. & Asofsky, R. A. (1973) A paradoxical effect of antithymocyte sera upon the thymus. Nature 243, 39. Cantor, H. & Boyse, E. A. (1975a) Functional subclasses of T lymphocytes bearing different Ly antigens. i. The generation of functionally distinct T cell subclasses is a differentiative process independent of antigen. J. Exp. Med. 141, 1375. Cantor, H. & Boyse, E. A. (1975b) Functional subclasses of T lymphocytes bearing different Ly antigens, n. Cooperation between subclasses of Ly+ cells in the generation of killer activity. J. Exp. Med. 141, 1390. Cantor, H. & Boyse, E. A. (1976) Regulation of cellular and humoral immunity by T cell subclasses. in: Origins of Lymphocyte Diversity-XLi Cold Spring Harbor Symposium on Quantitative Biology (Cold Spring Harbor Laboratory of Quantitative Biol. Pub., New York ). (in press). Cantor, H. & Jandinski, J. (1974) The relationship of cell division to the generation of cytotoxic activity in mixed lymphocyte culture. J. Exp. Med. 140, 1712. Cantor, H., Shen, F. W. & Boyse, E. A. (1976) Separation of helper T cells from suppressor T cells expressing different Ly components, ii. Activation by antigen: after immunization antigen specific suppressor and helper activities are mediated by distinct T-cell subclasses. J. Exp. Med. 143, 1391. Cantor, H. & Weissman, I. (1976) Development and function of subpopulations of thymocytes and peripheral T lymphocytes. Progr. Allergy 20, 1. Dukor, P., Miller, J. F. A. P., House, W. & Allman, V. (1965) Regulation of thymus grafts. i. Histological and cytological aspects.. Transplant. 3, 639. El-Arini, M. O. & Osoba, D. (1973) Differentiation of thymus-derived cells from precursors in mouse bone marrow. J. Exp. Med. 137, 821. Feldmann, M., Beverley, P. C. L., Dunkley, M. & Kontiainen, S. (1975) Different Ly antigen phenotypes on helper and suppressor cells. Nature 258, 614. Fialkow, P. J. (1974) The origin and development of human tumors studied with cell markers. N. Eng. J. Med. 291, 26. Ford, C.E., Micklem, H. S., Evans, E. P., Gray, J. G. & Ogden, D.A. (1966) The inflow of bone marrow cells to the thymus. Ann. N.Y. Acad. Sci. 129, 283. Goldstein, G. (1976) Radioimmunoassay for thymopoietin. J. immunol. (in press). Goldstein, G., Scheid, M. P., Hammerling, U., Boyse, E. A., Schlesinger, D. H. & Niall, H. D. (1975) Isolation of a polypeptide which has lymphocyte differentiating properties and is probably represented universally in living cells. Proc. Nat. Acad. Sci. USA 72, 11. Gurden, J. B. (1962) Developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. J. Embryol. 10, 622. Hammerling, U., Chin, A. F. & Abbott, J. (1976) Ontogeny of murine B lymphocytes: Sequence of B-cell differentiation from surface-immunoglobulin-negative precursors to plasma cells. Proc. Natl. Acad. Sci. 6, 2008. Harboe, M., Osterland, C. K., Mannik, M. & Kunkel, H. G. (1962) Genetic factors of human gamma globulins in myeloma proteins. J. Exp. Med. 116, 719. Huber, B., Cantor, H., Shen, F.W. & Boyse, E. A. (1976a) Independent differentiative pathways of Ly1 and Ly23 subclasses of T cells: Experimental production of mice deprived of selected T cell subclasses. J. Exp. Med. 144, 1128. Huber, B., Devinsky, O., Gershon, R. K. & Cantor, H. (1976b) Cell-mediated immunity: delayed type hypersensitivity and cytotoxic responses are mediated by different T cell subclasses. J. Exp. Med. 143, 1424. Huber, B., Gershon, R. K. & Cantor, H. (1976c) Identification of a B-cell surface structure involved in antigen-dependent triggering: absence of this structure on B cells from CBA/N mutant mice. J. Exp. Med. (in press). Jacob, F. & Monod, J. (1961) On the regulation of gene activity. Cold Spring Harbor Symposium Quantitative Biology 26, 193. Jandinski, J., Cantor, H., Tadakuma, T., Peavy, D. L. & Pierce, C. W. (1976) Separation of helper T cells from suppressor T cells expressing different Ly components. i. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses. J. Exp. Med. 143, 1382. Jeejeebhoy, H. F. (1970) The effect of heterologous anti-lymphocyte serum on lymphocytes of thymus and bone marrow origin. J. Exp. Med. 132, 963. Kisielow, P., Hirst, J., Shiku, H., Beverley, P. C. L., Hoffman, M. K., Boyse, E. A. & Oettgen, H. F. (1975) Ly antigens: markers for functionally distinct subsets of thymus-derived lymphocytes of the mouse. Nature (Lond.) 253, 219. Komoro, K., Goldstein, G. & Boyse, E. A. (1975) Thymus-repopulating capacity of cells that can be induced to differentiate to T cells in vitro. J. immunol. 115, 195. Krakow, J. S., Coutsogeorgopoulos, C. & Canellakis, E. S. (1962) Studies of the incorporation of deoxynucleotides and ribonucleotides into deoxynucleic acid. Bio-chem. Biophys. Acta 55, 639. Mandel, T. E. & Russell, P. J. (1971) Differentiation of foetal mouse thymus ultra-structure of organ cultures and of subcapsular grafts. Immunology 21, 659. Moore, M. A. S. & Owen, J. J. T. (1967) Experimental studies on the development of the thymus. J. Exp. Med. 126, 715. Ohno, S. (1966) Cytologic and genetic evidence of somatic segregation in mammals, birds, and fishes. in: Phenotypic expression in vitro. Vol. 2, PUBLICation of the tissue culture association. Baltimore , Williams and Wilkins, Co.. Owen, J. J. T. & Raff, M. C. (1970) Studies on the differentiation of thymus-derived lymphocytes. J. Exp. Med. 132, 1216. Owen, J. J. T. & Ritter, M. A. (1969) Tissue interaction in the development of thymus lymphocytes. J. Exp. Med. 129, 431. Pernis, B., Chiappino, G., Kelus, A. S. & Gell, P. G. H. (1965) Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues. J. Exp. Med. 122, 853. Scheid, M. P., Goldstein, G., Hammerling, U. & Boyse, E. A. (1975) Induction of T and B lymphocyte differentiation in vitro. in: Membrane Receptors of Lymphocytes. (North Holland, Pub. Co.). p. 353. Scher, I., Ahmed, A., Strong, D. M., Steinberg, A. D. & Paul, W. E. (1975) X-linked B-lymphocyte immune defect in CBA/N mice. i. Studies of the function and composition of spleen cells. J. Exp. Med. 141, 788. Scher, I., Steinberg, A. D., Berning, A. K. & Paul, W.E. (1975) X-linked B-lymphocyte immune defect in CBA/N mice. n. Studies of the mechanisms underlying the immune defect. J. Exp. Med. 142, 637. Schimpl, A. & Wecker, E. (1975) A third signal B cell activation given by TRF. Transplant. Rev. 23, 176. Schlesinger, D. H. & Goldstein, G. (1975) The amino acid sequence of thymopoietin ii. Cell 5, 361. Schlesinger, D. H., Goldstein, G., Scheid, M. P. & Boyse, E. A. (1975) Chemical synthesis of a peptide fragment of thymopoeitin ii that induces selective T-cell differentiation. Cell 5, 367. Shen, F. W., Boyse, E. A. & Cantor, H. (1975) Preparation and use of Ly antisera. Immunogenetics 2, 591. Shiku, H., Kisielow, P., Bean, M. A., Takahashi, T., Boyse, E. A., Oettgen, H. F. & Old, L. J. (1975) Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro: evidence for functional heterogeneity related to surface phenotype of T cells. J. Exp. Med. 141, 227. Silverstone, A. E., Cantor, H., Goldstein, G. & Baltimore, D. (1976) Terminal deoxynucleotidyl transferase is found in prothymocytes. J. Exp. Med. 144, 543. Storrie, B., Goldstein, G., Boyse, E. A. & Hammerling, U. (1976) Differentiation of thymocytes: Evidence that induction of the surface phenotype requires transcription and translation. J. immunol. 116, 1358. Stutman, O., Yunis, E. J. & Good, R. A. (1969) Carcinogen induced tumors of the thymus. iV. Humoral influences of normal thymus and functional thymomas and influence of post-thymectomy period on restoration. J. Exp. Med. 130, 809. Tada, T. & Taniguchi, M. (1976) The suppressive T cell factor as an i region gene product: Properties and the subregion assignment. in: Origins of Lymphocyte Diversity-XLi Cold Spring Harbor Symposium on Quantitative Biology (Cold Spring Harbor Laboratory of Quantitative Biol. Pub., New York ). (in press). Tada, T., Taniguchi, M. & Takemori, T. (1976) Properties of primed suppressor cells and their products. Transplant. Rev. 26. Tonegawa, S., Hozumi, N., Matthyssens, G. & Schuller, R. (1976) Somatic changes in content and context of immunoglobulin genes. in: Origins of Lymphocyte Diversity-XLi Cold Spring Harbor Symposium on Quantitative Biology (Cold Spring Harbor Symposium on Quantitative Biology (Cold Spring Harbor Laboratory of Quantitative Biol. Pub., New York ). (in press). Turpen, J. B., Volpe, E. P. & Cohen, N. (1973) Ontogeny and peripheralization of thymic lymphocytes. Science 182, 931. Weissman, I. L. (1973) Thymus cell maturation. Studies on the origin of cortisone resistant thymic lymphocytes. J. Exp. Med. 137, 504. Wu, A. M., Till, J. E., Simonovitch, K. & McCulloch, E.A. (1968) Cytological evidence for a relationship between normal hematopoietic colony-forming cells and cells of the lymphoid system. J. Exp. Med. 127, 455. Yoneda, M. & Bollum, F. J. (1965) Deoxynucleotide-polymerizing enzymes of calf thymus gland. i. Large scale purification of terminal and replicative deoxynucleotidyl transferase. J. Biol. Chem. 240, 3385. Citing Literature Volume33, Issue1January 1977Pages 105-124 ReferencesRelatedInformation