Spray drying of griseofulvin solution forming its solvate.
1988; Pharmaceutical Society of Japan; Volume: 36; Issue: 6 Linguagem: Inglês
10.1248/cpb.36.2193
ISSN1347-5223
AutoresYasuyuki Tsuda, Mariko Ishida, Etsuko Suzuki, Keiji Sekiguchi,
Tópico(s)Chromatography in Natural Products
ResumoA spray drying process was introduced into our method of particle size reduction by "solvation and desolvation" for the purpose of producing spherical particles with a large effective surface area. By solvate formation and successive desolvation in a single process of spray drying, preparation of spherical particles, which consist of primary fines, was achieved.
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