In vivo He-3 MR images of guinea pig lungs.
1996; Radiological Society of North America; Volume: 199; Issue: 3 Linguagem: Inglês
10.1148/radiology.199.3.8638019
ISSN1527-1315
AutoresRobert D. Black, H. Middleton, G. D. Cates, Gary P. Cofer, Bastiaan Driehuys, W. Happer, Laurence W. Hedlund, G. Allan Johnson, Mark D. Shattuck, J. C. Swartz,
Tópico(s)Advanced MRI Techniques and Applications
ResumoThe authors imaged the lungs of live guinea pigs with hyperpolarized (HP) helium-3 as a magnetic resonance (MR) signal source. HP He-3 gas produced through spin exchange with rubidium metal vapor was delivered through an MR-compatible, small-animal ventilator. Two- and three-dimensional lung images acquired with ventilation-gated, radial k-space sampling showed complete ventilation of both lungs. All images were of high quality, demonstrating that HP He-3 allows high-signal-intensity MR imaging in living systems.
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