On the lithium dimethylcuprate induced conversion of propargylic esters into allenes using a steroidal C/D fragment derived from vitamin D3 as a stereochemical probe.
1982; Elsevier BV; Volume: 23; Issue: 27 Linguagem: Inglês
10.1016/s0040-4039(00)87437-7
ISSN1873-3581
AutoresAlberto Haces, E. M. G. A. VAN KRUCHTEN, William H. Okamura,
Tópico(s)Catalytic Alkyne Reactions
ResumoThe reactions of (CH3)2CuLi with various C-8 epimeric propargylic esters derived from Grundmann's ketone, a C/D steroid fragment originating from vitamin D3, lead to the corresponding allenes, the stereochemistry of which indicate a preferred anti 1,3-substitution.
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