A Phenomenon of Macrophage Aggregation Activity in Sera of Patients With Exfoliative Erythroderma, Erythema Multiforme, and Erythema Nodosum
1973; Elsevier BV; Volume: 60; Issue: 5 Linguagem: Inglês
10.1111/1523-1747.ep12722989
ISSN1523-1747
AutoresGerald G. Krueger, William L. Weston, E. George Thorne, Mitchell J Mandel, Robert J. Jacobs,
Tópico(s)Cytokine Signaling Pathways and Interactions
ResumoAggregation of guinea-pig macrophages within 6 hr of incubation was detected in human sera from patients with erythroderma, erythema multiforme, and erythema nodosum, but not in controls or patients with other diseases, in addition, all seven erythrodermic patients showed a substance in their sera that produced erythema in guinea-pig skin. This phenomenon may result from overproduction of mediators of cellular immunity.
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