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Clinical value of serum squamous cell carcinoma antigen in the management of sinonasal inverted papilloma

2004; Wiley; Volume: 27; Issue: 1 Linguagem: Inglês

10.1002/hed.20115

1097-0347

Ryuji Yasumatsu, Torahiko Nakashima, Muneyuki Masuda, Yuichiro Kuratomi, Hideki Shiratsuchi, Naoya Hirakawa, Kichinobu Tomita, Tomoya Yamamoto, Shizuo Komune,

Bone Tumor Diagnosis and Treatments

Head & NeckVolume 27, Issue 1 p. 44-48 Regular Article Clinical value of serum squamous cell carcinoma antigen in the management of sinonasal inverted papilloma Ryuji Yasumatsu MD, Corresponding Author Ryuji Yasumatsu MD [email protected] Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, Japan The Division of Newborn Medicine, Children's Hospital, Harvard Medical School, 300 Longwood Ave., Enders 950, Boston, MA 02115The Division of Newborn Medicine, Children's Hospital, Harvard Medical School, 300 Longwood Ave., Enders 950, Boston, MA 02115Search for more papers by this authorTorahiko Nakashima MD, Torahiko Nakashima MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorMuneyuki Masuda MD, Muneyuki Masuda MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorYuichiro Kuratomi MD, Yuichiro Kuratomi MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorHideki Shiratsuchi MD, Hideki Shiratsuchi MD Department of Otorhinolaryngology, National Kyushu Medical Center, Fukuoka, JapanSearch for more papers by this authorNaoya Hirakawa MD, Naoya Hirakawa MD Department of Otorhinolaryngology, National Kyushu Medical Center, Fukuoka, JapanSearch for more papers by this authorKichinobu Tomita MD, Kichinobu Tomita MD The Division of Head and Neck, National Kyushu Cancer Center, Fukuoka, JapanSearch for more papers by this authorTomoya Yamamoto MD, Tomoya Yamamoto MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorShizuo Komune MD, Shizuo Komune MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this author Ryuji Yasumatsu MD, Corresponding Author Ryuji Yasumatsu MD [email protected] Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, Japan The Division of Newborn Medicine, Children's Hospital, Harvard Medical School, 300 Longwood Ave., Enders 950, Boston, MA 02115The Division of Newborn Medicine, Children's Hospital, Harvard Medical School, 300 Longwood Ave., Enders 950, Boston, MA 02115Search for more papers by this authorTorahiko Nakashima MD, Torahiko Nakashima MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorMuneyuki Masuda MD, Muneyuki Masuda MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorYuichiro Kuratomi MD, Yuichiro Kuratomi MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorHideki Shiratsuchi MD, Hideki Shiratsuchi MD Department of Otorhinolaryngology, National Kyushu Medical Center, Fukuoka, JapanSearch for more papers by this authorNaoya Hirakawa MD, Naoya Hirakawa MD Department of Otorhinolaryngology, National Kyushu Medical Center, Fukuoka, JapanSearch for more papers by this authorKichinobu Tomita MD, Kichinobu Tomita MD The Division of Head and Neck, National Kyushu Cancer Center, Fukuoka, JapanSearch for more papers by this authorTomoya Yamamoto MD, Tomoya Yamamoto MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this authorShizuo Komune MD, Shizuo Komune MD Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, JapanSearch for more papers by this author First published: 30 September 2004 https://doi.org/10.1002/hed.20115Citations: 22Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Background. Although sinonasal inverted papilloma (IP) is a rare benign tumor, it has a tendency to recur and is sometimes associated with squamous cell carcinoma (SCC). Therefore, postoperative long-term follow-up of these patients is recommended. We previously reported that serum SCC antigen might be a useful tumor marker for sinonasal IP. In this study, we investigated whether serum SCC antigen level has a correlation with disease status and is useful in the early detection of recurrent disease. Methods. Blood samples for the analysis of serum SCC antigen were taken from 28 IP patients before and after surgical treatment. Results. Twenty-five (89%) of 28 cases showed evaluated serum SCC antigen levels above the upper limit. This marker level decreased in all cases after surgical resection. Four of these patients had a recurrence. None of the patients with recurrent tumor showed symptoms at the time of detection of their recurrent tumor, and recurrence was discovered from elevated levels of SCC antigen. Conclusions. Serum SCC antigen level has a correlation with disease status of IP and has a potential to serve as a useful tool for monitoring the course of disease. SCC antigen is a reliable tumor marker in the management of sinonasal IPs. © 2004 Wiley Periodicals, Inc. Head Neck 27: 44–48, 2005 Citing Literature Volume27, Issue1January 2005Pages 44-48 RelatedInformation