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The value of CHADS2 score in predicting new-onset atrial fibrillation in Chinese patients with acute myocardial infarction

2014; Elsevier BV; Volume: 176; Issue: 3 Linguagem: Inglês

10.1016/j.ijcard.2014.07.210

1874-1754

Xiaowei Zhang, Guangping Li, Zhiqiang Zhao, Yanmin Xu, Tong Liu,

Cardiac Arrhythmias and Treatments

Previous studies have shown that new-onset atrial fibrillation (AF) in the setting of acute myocardial infarction (AMI) was associated with increased in-hospital and long term mortality [ 1 Ruwald A.C. Bloch Thomsen P.E. Gang U. et al. New-onset atrial fibrillation predicts malignant arrhythmias in post-myocardial infarction patients—a Cardiac Arrhythmias and RIsk Stratification after acute Myocardial infArction (CARISMA) substudy. Am Heart J. 2013; 166: 855-863 Abstract Full Text Full Text PDF PubMed Scopus (33) Google Scholar , 2 Rene A.G. Généreux P. Ezekowitz M. et al. Impact of atrial fibrillation in patients with ST-elevation myocardial infarction treated with percutaneous coronary intervention (from the HORIZONS-AMI [Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction] trial). Am J Cardiol. 2014; 113: 236-242 Abstract Full Text Full Text PDF PubMed Scopus (71) Google Scholar ]. Therefore, it was crucial to recognize the patients with AMI who were on the increased risk for developing new-onset AF. CHADS2 score (congestive heart failure, hypertension, age ≥ 75 years, diabetes and previous stroke or transient ischemic attack) was a very useful and convenient scoring system, which was widely used for the stroke risk stratification in the patients with non-valvular AF [ [3] Gage B.F. Waterman A.D. Shannon W. et al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001; 285: 2864-2870 Crossref PubMed Scopus (4280) Google Scholar ]. Recently, CHADS2 score has been found to be associated with an increased risk of AF recurrence following catheter ablation [ [4] Chao T.F. Ambrose K. Tsao H.M. et al. Relationship between the CHADS(2) score and risk of very late recurrences after catheter ablation of paroxysmal atrial fibrillation. Heart Rhythm. 2012; 9: 1185-1191 Abstract Full Text Full Text PDF PubMed Scopus (60) Google Scholar ] and the first-time appearance of AF in patients with frequent supraventricular extrasystoles [ [5] Suzuki S. Sagara K. Otsuka T. et al. Usefulness of frequent supraventricular extrasystoles and a high CHADS2 score to predict first-time appearance of atrial fibrillation. Am J Cardiol. 2013; 111: 1602-1607 Abstract Full Text Full Text PDF PubMed Scopus (56) Google Scholar ]. In a recent study published in the International Journal of Cardiology, Ruwald et al. enrolled 297 post-MI patients from the CARISMA study with left ventricular ejection fraction (LVEF) ≤40%. They demonstrated that CHADS2 score efficiently identified the patients at high risk for cardiac arrhythmias including new-onset AF in the post-myocardial infarction (MI) setting [ [6] Ruwald A.C. Gang U. Thomsen P.E. et al. The predictive value of CHADS2 risk score in post myocardial infarction arrhythmias — a Cardiac Arrhythmias and RIsk Stratification after Myocardial infArction (CARISMA) substudy. Int J Cardiol. 2014; 173: 441-446 Abstract Full Text Full Text PDF PubMed Scopus (14) Google Scholar ]. However, there is limited data regarding the predictive value of CHADS2 score for the development of new-onset AF in Chinese patients with AMI. Therefore, we aimed to evaluate whether CHADS2 score could be utilized as an independent predictor for the development of new-onset AF in Chinese patients with AMI.