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Permethrin and Ivermectin for Scabies

2010; Massachusetts Medical Society; Volume: 362; Issue: 8 Linguagem: Inglês

10.1056/nejmct0910329

1533-4406

Bart J. Currie, James McCarthy,

Bird parasitology and diseases

A 4-year-old boy is brought to a health center with sores on his arms and legs. He and several siblings receive a diagnosis of scabies. Crusted scabies is diagnosed in an elderly aunt in the same household. The family members are treated with topical permethrin, which disrupts the function of voltage-gated sodium channels in arthropods. The aunt is treated with oral ivermectin, which disrupts the function of chloride ion channels.