Portal de Periódicos da CAPES

Molecular Analysis of the Interleukin‐2 System

1986; Wiley; Volume: 92; Issue: 1 Linguagem: Inglês

10.1111/j.1600-065x.1986.tb01497.x

1600-065X

Tadatsugu Taniguchi, Hiroshi Matsui, Takashi Fujita, Masanori Hatakeyama, Nobukazu Kashima, Akira Fuse, Junji Hamuro, Chikako Nishi‐Takaoka, Gen Yamada,

NF-κB Signaling Pathways

Immunological ReviewsVolume 92, Issue 1 p. 121-134 Molecular Analysis of the Interleukin-2 System Tadatsugu Taniguchi, Tadatsugu Taniguchi 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565. 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorHiroshi Matsui, Hiroshi Matsui 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170. 3Central Research Laboratories, Ajinomoto Co. Inc., Totsuka-ku, Yokohama 224, Japan.Search for more papers by this authorTakashi Fujita, Takashi Fujita 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565. 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorMasanori Hatakeyama, Masanori Hatakeyama 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565.Search for more papers by this authorNobukazu Kashima, Nobukazu Kashima 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170. 3Central Research Laboratories, Ajinomoto Co. Inc., Totsuka-ku, Yokohama 224, Japan.Search for more papers by this authorAkira Fuse, Akira Fuse 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorJunji Hamuro, Junji Hamuro 3Central Research Laboratories, Ajinomoto Co. Inc., Totsuka-ku, Yokohama 224, Japan.Search for more papers by this authorChikako Nishi-Takaoka, Chikako Nishi-Takaoka 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorGen Yamada, Gen Yamada 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565. 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this author Tadatsugu Taniguchi, Tadatsugu Taniguchi 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565. 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorHiroshi Matsui, Hiroshi Matsui 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170. 3Central Research Laboratories, Ajinomoto Co. Inc., Totsuka-ku, Yokohama 224, Japan.Search for more papers by this authorTakashi Fujita, Takashi Fujita 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565. 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorMasanori Hatakeyama, Masanori Hatakeyama 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565.Search for more papers by this authorNobukazu Kashima, Nobukazu Kashima 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170. 3Central Research Laboratories, Ajinomoto Co. Inc., Totsuka-ku, Yokohama 224, Japan.Search for more papers by this authorAkira Fuse, Akira Fuse 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorJunji Hamuro, Junji Hamuro 3Central Research Laboratories, Ajinomoto Co. Inc., Totsuka-ku, Yokohama 224, Japan.Search for more papers by this authorChikako Nishi-Takaoka, Chikako Nishi-Takaoka 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this authorGen Yamada, Gen Yamada 1Institute for Molecular and Cellular Biology, Osaka University, Suita-shi. Osaka 565. 2Department of Biochemistry, Cancer institute. ToshJma-ku. Tokyo 170.Search for more papers by this author First published: August 1986 https://doi.org/10.1111/j.1600-065X.1986.tb01497.xCitations: 59AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Cepko, C. L., Roberts, B. E. & Mulligan, R. C. (1984) Construction and application of a highly transmissible murine retrovirus shuttle vector. Cell 31, 1053. Clark, S., C, Arya, S. K., Wong-Staal, F., Matsumoto-Kobayashi, M., Kay, R. M., Kaufman, R. J., Brown, E. L., Schocmaker, C., Copeland, T., Droszlan, S., Smith, K., Sarngadharam, M. G., Linder, S.G. & Gallo, R. (1984) Human T-cell growth factor: Partial amino acid sequence, cDNA cloning, and organization and expression in normal and leukemic cells. Proc. Natl. Acad. Sci. USA 81, 2543. Cosman, D., Cerretti, D. P., Larsen, A., Park, L., March, C., Dower, S., Gillis, S. & Urdall, D. (1984) Cloning, sequence and expression of human interleukin-2 receptor. Nature 312, 768. Devos, R., Plaetinck, G., Cheroutre, H., Simons, G., Degrave, W., Tavernier, J., Remaut, E. & Fiers, W. (1983) Molecular cloning of human interleukin 2 cDNA and its expression in E. coli. Nucleic Acids Res. 11, 4307. Efrat, S., Pilos, S. & Kaempfer, R. (1982) Kinetics of induction and molecular size of mRNAs encoding human interleukin-2 and γ-interferon. Nature 297, 236. Fujita, T., Takaoka, C. Matsui, H. & Taniguchi, T. (1983) Structure of the human interleukin 2 gene. Proc. Natl. Acad. Sci. USA 80, 7437. Fujita, T. Shibuya, H., Ohashi, T., Yamanishi, K. & Taniguchi, T. (1986) Regulation of human interleukin-2 gene; Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes. Cell (in press). Fuse, A., Fujita, T., Yasumitsu, H., Kashima, N., Hasegawa, K. & Taniguchi, T. (1984) Organization and structure of the mouse interleukin-2 gene. Nucleic Acids Res. 12, 9323. Gillis, S., Baker, P. E., Union, N. A. & Smith, K. A. (1979) The in vitro generation and sustained culture of nude cytotoxic T-lymphocytes. J. Exp. Med. 149, 1460. Gillis, S., Ferm, M. M., Ou, W. & Smith, K. A. (1978) T-cell growth factor: Parameters of production and a quantitative microassay for activity. J. Immunol. 120, 2027. Gillis, S. & Smith, K. A. (1977) Long term culture of tumor-specific cytotoxic T-cells. Nature 268, 154. Greene, W., Robb, R. J., Svetlik, P. B., Rusk, G. M., Depper, J. M. & Leonard, W. J. (1985) Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells. J. Exp. Med. 162, 363. Grimm, E. A., Mazumder, A., Zharg, H. Z. & Rosenberg, S. A. (1982) Lymphokine-activated killer cell phenomenon: lysis of natural killer-resistant fresh solid tumor cells by interkeukin-2-activated autologous human peripheral blood lymphocytes. J. Exp. Med. 155, 1823. Hansen, J. A., Martin, P. J. & Nowinski, R. C. (1980) Monoclonal antibodies identifying a novel T-cell antigen and la antigens of human lymphocytes. Immunogenetics 10, 247. Harpold, M. M., Dobner, R. R., Evans, R. M. & Bancroft, F. C. (1978) Construction and identification by positive hybridization-translation of a bacterial plasmid containing a rat growth hormone structural gene sequence. Nucleic Acids Res. 5, 2039. Hatakeyama, M., Minamoto, S., Uchiyama, T., Hardy, R. R., Yamada, G. & Taniguchi, T. (1985) Reconstitution of functional receptor for human interleukin-2 in mouse cells. Nature 318, 467. Henny, C. S., Kuribayashi, K., Kern, D. E. & Gillis, S. (1981) Interieukin-2 augments natural killer cell activity. Nature 291, 335. Holbrook, N. J., Smith, K. A., Fornace, A. J.Jr., Comeau, C. M., Wilskocil, R. L. & Crabtree, G. (1984) T-cell growth factor: Complete nucleotide sequence and organization of the gene in normal and malignant cells. Proc. Natl. Acad. Sci. USA 81, 1634. Kashima, N., Nishi-Takaoka, C. Fujita, T., Taki, S., Yamada, G., Hamuro, J. & Taniguchi, T. (1985) Unique structure of murine interleukin-2 as deduced from cloned cDNAs. Nature 313, 402. Kishi, H., Inui, S., Muraguchi, A., Hirano, T., Yamamura, Y. & Kishimoto, T. (1985) Induction of IgG secretion in a human B cell clone with recombinant IL2. J. Immunol. 134, 3104. Land, H., Grez, N., Hansen, H., Lindermaier, W. & Schuctz, G. (1981) 5–terminal sequences of eukaryotic mRNA can be cloned with high efficiency. Nucleic Acids Res. 9, 2251. Leonard, W. J., Depper, J. M., Crabtrec, G. R., Rudikoff, S., Pumphrey, J., Robh, R. J., Kronke, M., Svetlik, P. B., Peffer, N. J., Waldmann, T. A. & Greene, W. C. (1984) Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature 311, 626. Leonard, W.J., Depper, J. M., Robb, R. J., Waldmann, T. A. & Greene, W. C. (1983) Characterization of the human receptor for T-cell growth factor. Proc. Natl. Acad. Sci. USA 80, 6957. Matsui, H., Fujita, T., Nishi-Takaoka, C., Hamuro, J. & Taniguchi, T. (1985) Molecular cloning and expression of the human interleukin 2 gene. In: Lymphokines, E. Pick eds.., Vol, 12, p. 1. Academic Press. New York . Mond, J. J., Thompson, C. T., Einkelman, F. D., Farrar, J., Schaefer, M. & Robb, R. J. (1985) Affinity-purified interleukin-2 induces proliferation of large but not small B cells. Proc. Natl. Acad. Sci. USA 82, 1518. Morgan, D. A., Ruscetti, F. W. & Gallo, R. (1976) Selective in vitro growth of T-lymphocytes from normal human bone marrows. Science 193, 1007. Mulligan, R.C. & Berg, P. (1981) Selection for animal cells that express the Escherichia coli gene coding for xanthinc-guanine phosphoribosyl transferase. Proc. Natl. Acad. Sci. USA 78, 2072. Nagala, S., Taira, H., Hall, A., Johnsrud, L., Streuli, M., Essödi, J., Boll, W., Catitell, & Weissmann, C. (1980) Synthesis in E. coli of a polypeptide with human leukocyte interferon activity. Nature 284, 316. Nikaido, T., Shimizu, A., Ishida, N., Sabe, H., Teshigawara, K., Maeda, M., Uchiyama, T., Yodoi, J. & Honjo, T. (1984) Molecular cloning of cDNA encoding human inter-leukin-2 receptor. Nature 311, 631. Robb, R. J., Greene, W. C. & Rusk, C. M. (1984b). Low and high affinity cellular receptors for inlerleukin 2. Implications for the level of Tac antigen. J. Exp. Med. 160, 1126. Robb, R. J., Kutny, R. M., Panico, M., Morris, H. R. & Chowdhry, V. (1984a) Amino acid sequence and post-translational modifications of human interleukin 2. Proc. Natl. Acad. Sci. USA 81, 6486. Rosenberg, S. A., Lotzc, M. T., Muul, L. M., Leitman, S., Chang, A. E., Ettinghausen, S. E., Matory, Y. L., Skibber, J. M., Shiloni, E., Vetto, J. T., Seipp, C. A., Simpson, C. & Reichert, C. M. (1985) Observations on the systemic administration of autologous lymphokine-activated killer ceils and recombinant interleukin-2 to patients with meta-static cancer. New Engl, J. Med. 313, 1485. Shows, T., Eddy, R., Haley, L., Byers, M., Henry, M., Fujita, T., Matsui, T. & Taniguchi, T. (1984) Interleukin 2 (IL2) is assigned to human chromosome 4. Som. Cell Mol. Genet. 10, 315. Sieff, C. A., Emerson, S. G., Donahue, R. E., Nathan, D. G., Wang, E. A., Wong, G. G. & Clark, S. C. (1985) Human recombinant granulocyte-maerophage colony-stimulating factor: a multilineage hematopoietin. Science 230, 1171. Smith, S. A. (1980) T-cell growth factor, Immunol. Rev. 51, 337. Smith, K. A. (1984) Interleukin 2. Ann. Rev. Immunol. 2, 319. Sporn, M. B. & Roberts, A. B. (1985) Autocrine growth factors and cancer. Nature 313, 745. Sugamura, K., Nakai, S., Fujii, M. & Hinuma, Y. (1985) Interleukin 2 inhibits in vitro growth of human T cell lines carrying retroviruses. J. Exp. Med. 161, 1243. Taniguchi, T., Fujii-Kuriyama, Y. & Muramatsu, M. (1980) Molecular cloning of human interferon cDNA. Proc. Natl. Acad. Sci. USA 11, 4003. Taniguchi, T., Malsu, J. H., Fujita, T. Takaoka, C., Kashima, N., Yoshimoto, R. & Hamuro, J. (1983) Structure and expression of a cloned cDNA for human interleukin-2. Nature 302, 305. Taniguchi, T., Sakai, M., Fujii-Kariyama, Y., Muramatsu, M., Kobayashi, S., & Sudo, T (1979) Construction and identification of a bacterial plasmid containing the human fibroblast interferon gene sequence. Proc. Jpn. Acad. 55, 464. Uchiyama, T., Nelson, D. L., Fleisher, T. A. & Waidmann. T (1981) A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells 1. Production of anti-Tac monoclonal antibody and distribution of Tac(+) cells. J. Immunol. 126, 1393. Wang, A., Lu, S-D. & Mark, D. F. (1984) Site-specific mutagenesis of the human interieukin-2 gene: Structure-function analysis of the cysteine residues. Science 224, 1431. Yokota, T., Arai, N., Lee, F., Rennick, D., Mosman, T. & Arai, K. (1985) Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones; Expression of T-cell growth-factor activity after transfection of monkey cells. Proc. Natl. Acad. Sci. USA 82, 68. Citing Literature Volume92, Issue1August 1986Pages 121-134 ReferencesRelatedInformation