Oral cancer development in patients with oral lichen planus
1993; Wiley; Volume: 22; Issue: 9 Linguagem: Inglês
10.1111/j.1600-0714.1993.tb00134.x
ISSN1600-0714
AutoresN. Barnard, C Scully, J.W. Eveson, Susan Cunningham, Stephen Porter,
Tópico(s)Head and Neck Cancer Studies
ResumoThere has been considerable controversy as to whether oral lichen planus (LP) has a premalignant potential. This study retrospectively examined the records of 241 British patients with histologically confirmed LP seen during the 10‐year period 1982–92. Nine patients (3.7%) were known to have developed well‐differentiated invasive carcinoma or carcinoma in situ in an area of LP. Most carcinomas at presentation were in areas of atrophic and/or erosive LP, 6 were in patients older than 65 years, and 6 were on the tongue. The results support a small but clinically important premalignant potential for LP.
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