Artigo Revisado por pares

EVIDENCE FOR MULTIPLE STRUCTURAL GENES FOR THE GAMMA‐CHAIN OF HUMAN FETAL HEMOGLOBIN IN HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN*

1969; Wiley; Volume: 165; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1969.tb27802.x

ISSN

1749-6632

Autores

T. H. J. Huisman, W. A. Schroeder, Andrée M. Dozy, J. Roger Shelton, Joan B. Shelton, E.M. Boyd, Gerald Apell,

Tópico(s)

Prenatal Screening and Diagnostics

Resumo

Annals of the New York Academy of SciencesVolume 165, Issue 1 p. 320-331 EVIDENCE FOR MULTIPLE STRUCTURAL GENES FOR THE GAMMA-CHAIN OF HUMAN FETAL HEMOGLOBIN IN HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN* T. H. J. Huisman, T. H. J. Huisman Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorW. A. Schroeder, W. A. Schroeder Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorAndrée M. Dozy, Andrée M. Dozy Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorJ. R. Shelton, J. R. Shelton Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorJoan B. Shelton, Joan B. Shelton Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorEvalyn M. Boyd, Evalyn M. Boyd Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorG. Apell, G. Apell Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this author T. H. J. Huisman, T. H. J. Huisman Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorW. A. Schroeder, W. A. Schroeder Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorAndrée M. Dozy, Andrée M. Dozy Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorJ. R. Shelton, J. R. Shelton Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorJoan B. Shelton, Joan B. Shelton Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorEvalyn M. Boyd, Evalyn M. Boyd Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this authorG. Apell, G. Apell Division of Protein Chemistry Department of Biochemistry Medical College of Georgia and Veterans Administration Hospital Augusta, Ga.; Division of Chemistry and Chemical Engineering † California Institute of Technology Pasadena, Calif.Search for more papers by this author First published: November 1969 https://doi.org/10.1111/j.1749-6632.1969.tb27802.xCitations: 61 * These studies were supported in part by grants (HE-02558 and HE-05168) from the National Institutes of Health, United States Public Health Service. † Contribution No. 3732. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Anson, M. L. & A. E. Mirsky 1930. Protein coagulation and its reversal. The preparation of insoluble globin, soluble globin, and heme. J. Gen. Physiol. 13: 469. Betke, K. & E. Kleihauer 1958. Fetaler und bleibender Blutfarbstof in Erythrozyten und Erythroblasten von menschlichen feten und neugeborenen. Blut 4: 241. Conley, C, L. D. J. Weatherall, S. N. Richardson, M. K. Shepard & S. Charache 1963. Hereditary persistence of fetal hemoglobin: A study of 79 affected persons in 15 Negro families in Baltimore. Blood 21: 261. Dozy, A. M., E. F. Kleihauer & T. H. J. Huisman 1968. Studies on the heterogeneity of hemoglobin. XIII. Chromatography of various human and animal hemoglobin types on DEAE-Sephadex. J. Chromatogr. 32: 723. Edington, G. M. & H. Lehmann 1955. Expression of the sickle-cell gene in Africa. Brit. Med. J. I: 1308, ii: 1328. Fessas, P. & G. Stamatoyannopoulos 1964. 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Evidence for multiple structural genes for the γ chain of human fetal hemoglobin. Proc. Nat. Acad. Sci. 60: 537. Thompson, R. B., J. W. Mitchener & T. H. J. Huisman 1961. Studies on the fetal hemoglobin in the persistent high Hb-F anomaly. Blood 18: 267. Wasi, P., S. Pootrakul & S. Na-Nakorn 1968. Hereditary persistence of foetal haemoglobin in a Thai family: The first instance in the Mongol race and in association with haemoglobin E. Brit. J. Haemat. 14: 501. Weatherall, D. J. 1965. The Thalassaemia Syndromes. Blackwell Scientific Publications. Oxford , England . Wintrobe, M. M. 1962. Clinical Hematology. 5th Edit. Lea & Febiger. Philadelphia , Pa . Zuckerkandl, E. 1964. Controller-gene diseases. J. Molec. Biol. 8: 128. Citing Literature Volume165, Issue1Second Conference on the Problems of Cooley's AnemiaNovember 1969Pages 320-331 ReferencesRelatedInformation

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