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Synthesis of β‐phenylethylamine derivatives VII: The enantiomers of erythro‐1‐(4′‐hydroxyphenyl)‐2‐(1″‐methyl‐2″‐phenoxyethylamino)‐propanol‐1

1961; Royal Netherlands Chemical Society; Volume: 80; Issue: 5 Linguagem: Inglês

10.1002/recl.19610800514

1878-7096

Johannes van Dijk, H. D. Moed,

Chemical Reactions and Isotopes

Abstract The resolution of racemic erythro ‐i‐(4′‐hydroxyphenyl)‐2‐(1″‐methyl‐2″‐phenoxyethylamino)propanol‐1 (Caa 40 Name used in the pharmacological tests. Commercial name “Duvadilan”, N.V. Philips‐Duphar. ) is described. The absolute configuration of the three asymmetric centres of the enantiomers is established.