THE EFFECTS ON CARDIAC MUSCLE OF β‐RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICS
1965; Wiley; Volume: 24; Issue: 2 Linguagem: Inglês
10.1111/j.1476-5381.1965.tb01719.x
ISSN2056-8177
AutoresA Morales-Aguilera, E. M. Vaughan Williams,
Tópico(s)Neuropeptides and Animal Physiology
ResumoBritish Journal of Pharmacology and ChemotherapyVolume 24, Issue 2 p. 332-338 Free Access THE EFFECTS ON CARDIAC MUSCLE OF β-RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICS A. MORALES-AGUILERÁ, A. MORALES-AGUILERÁ Department of Pharmacology, University of OxfordSearch for more papers by this authorE. M. VAUGHAN WILLIAMS, E. M. VAUGHAN WILLIAMS Department of Pharmacology, University of OxfordSearch for more papers by this author A. MORALES-AGUILERÁ, A. MORALES-AGUILERÁ Department of Pharmacology, University of OxfordSearch for more papers by this authorE. M. VAUGHAN WILLIAMS, E. M. VAUGHAN WILLIAMS Department of Pharmacology, University of OxfordSearch for more papers by this author First published: April 1965 https://doi.org/10.1111/j.1476-5381.1965.tb01719.xCitations: 90AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Black, J. W. & Stephenson, J. S. (1962). Pharmacology of a new adrenergic beta-receptor-blocking compound, Nethalide. Lancet, ii, 311–314. 10.1016/S0140-6736(62)90103-4 CASGoogle Scholar Bülbring, E. & Wajda, I. (1945). Biological comparison of local anaesthetics. J. Pharmacol. exp. Ther., 85, 78–84. CASPubMedWeb of Science®Google Scholar Gill, E. W. & Vaughan Williams, E. M. (1964). Local anaesthetic activity of the β-receptor antagonist, pronethalol. Nature (Lond), 201, 199. 10.1038/201199a0 CASPubMedWeb of Science®Google Scholar Goodford, P. J. & Vaughan Williams, E. M. (1962). Intracellular Na and K concentrations of rabbit atria, in relation to the action of quinidine. J. Physiol. (Lond), 160, 483–493. 10.1113/jphysiol.1962.sp006861 CASPubMedWeb of Science®Google Scholar Hutter, O. F. & Trautwein, W. (1956). Vagal and sympathetic effects on the pacemaker fibres in the sinus venosus of the heart. J. gen. Physiol., 39, 715–733. 10.1085/jgp.39.5.715 CASPubMedWeb of Science®Google Scholar Löfgren, N. (1948). Studies on Local Anaesthetics. Xylocaine, a new synthetic drug Stockholm: Ivar Haeggströms. Google Scholar Payne, J. P. & Senfield, R. M. (1964). Pronethalol in the treatment of ventricular arrhythmias during anaesthesia. Brit. med. J., i, 603–604. 10.1136/bmj.1.5383.603 Web of Science®Google Scholar Sekiya, A. & Vaughan Williams, E. M. (1963a). The effects of pronethalol, dichloroisoprenaline and disopyramide on the toxicity to the heart of ouabain and anaesthetics. Brit. J. Pharmacol., 21, 462–472. 10.1111/j.1476-5381.1963.tb02014.x CASPubMedWeb of Science®Google Scholar Sekiya, A. & Vaughan Williams, E. M. (1963b). A comparison of the antifibrillatory actions and effects on intracellular cardiac potentials of pronethalol, disopyramide and quinidine. Brit. J. Pharmacol., 21, 473–481. 10.1111/j.1476-5381.1963.tb02015.x CASPubMedWeb of Science®Google Scholar Stock, J. P. P. & Dale, N. (1963). Beta-adrenergic receptor blockade in cardiac arrhythmias. Brit. med. J., ii, 1230–1233. 10.1136/bmj.2.5367.1230 CASGoogle Scholar Szekeres, L. & Vaughan Williams, E. M. (1962). Antifibrillatory action. J. Physiol. (Lond), 160, 470–482. 10.1113/jphysiol.1962.sp006860 CASPubMedWeb of Science®Google Scholar Vaughan Williams, E. M. (1958a). The mode of action of quinidine on isolated rabbit atria interpreted from intracellular records. Brit. J. Pharmacol., 13, 276–287. 10.1111/j.1476-5381.1958.tb00903.x Web of Science®Google Scholar Vaughan Williams, E. M. (1958b). Some observations concerning the mode of action of acetylcholine on isolated rabbit atria. J. Physiol. (Lond), 140, 327–346. Google Scholar Vaughan Williams, E. M. (1959). The effect of changes in extracellular potassium concentration on the intracellular potentials of isolated rabbit atria. J. Physiol. (Lond), 146, 411–427. 10.1113/jphysiol.1959.sp006201 PubMedGoogle Scholar Vaughan Williams, E. M. & Sekiya, A. (1963). Prevention of arrhythmias due to cardiac glycosides by block of β-sympathetic receptors. Lancet, i, 420–421. Google Scholar Vaughan Williams, E. M. & Szekeres, L. (1961). A comparison of tests for antifibrillatory action. Brit. J. Pharmacol., 17, 424–432. 10.1111/j.1476-5381.1961.tb01129.x Google Scholar West, T. C. & Amory, D. W. (1960). Single fiber recording of the effects of quinidine at atrial and pacemaker sites in the isolated right atrium of the rabbit. J. Pharmacol. exp. Ther., 130, 183–193. CASPubMedWeb of Science®Google Scholar Citing Literature Volume24, Issue2April 1965Pages 332-338 ReferencesRelatedInformation
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