Phenylethylaminergic mechanisms in attention-deficit disorder
1991; Elsevier BV; Volume: 29; Issue: 1 Linguagem: Inglês
10.1016/0006-3223(91)90207-3
ISSN1873-2402
AutoresGlen B. Baker, Robert A. Bornstein, A. C. Rouget, S. Ashton, Jordyce C. Van Muyden, Ronald T. Coutts,
Tópico(s)Amino Acid Enzymes and Metabolism
ResumoUrinary excretion (24-hr) of β-phenylethylamine (PEA), phenylacetic acid (PAA), phenylalanine (Phe), and p-tyrosine (Tyr), and plasma levels of PAA, Phe, and Tyr were examined in 18 normal children and 26 children diagnosed as having attention-deficit hyperactivity disorder (ADHD). The results indicated that urinary excretion (expressed per g of creatinine) of free and total PEA was significantly lower in the ADHD patients, and plasma levels of Phe and Tyr were also decreased in the ADHD subjects compared with the normal controls.
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