2,3-dihydrojaborosalactone A, a withanolide from Acnistus breviflorus
1985; Elsevier BV; Volume: 24; Issue: 8 Linguagem: Inglês
10.1016/s0031-9422(00)82554-6
ISSN1873-3700
AutoresAdriana S. Veleiro, Gerardo Burton, Eduardo G. Gros,
Tópico(s)Phytochemicals and Medicinal Plants
ResumoFrom Acnistus breviflorus the new 27-hydroxy-5β,6β-epoxy-1-oxo-(22R)-witha-24-enolide (2,3-dihydrojaborosalactone A) as well as seven known withanolides, withaferin A, 2,3-dihydrowithaferin A, 6α-chloro-5β-hydroxywithaferin A, 5,6-deoxywithaferin A, jaborosalactone A, jaborosalactone D and jaborosalactone E were isolated and characterized by means of spectroscopic (1H NMR, 13 C NMR and mass spectral) methods. Depending on the extraction solvent (methanol or ethanol), a known artifact (3β-methoxy-2,3-dihydrowithaferin A) and the new 5α-methoxy-4,5-dihydrojaborosalactone B and 5α-ethoxy-4,5-dihydrojaborosalactone B were also isolated and characterized.
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