Efficient copper-catalyzed N-arylations of nitrogen-containing heterocycles and aliphatic amines in water
2010; Royal Society of Chemistry; Volume: 12; Issue: 6 Linguagem: Inglês
10.1039/c002172e
ISSN1463-9270
AutoresXufeng Li, Daoshan Yang, Yuyang Jiang, Hua Fu,
Tópico(s)Sulfur-Based Synthesis Techniques
ResumoA simple and efficient copper-catalyzed method has been developed for N-arylations of nitrogen-containing heterocycles and aliphatic amines in water. The protocol uses (1E,2E)-oxalaldehyde dioxime (OADO) as the ligand, and water as the solvent, and shows good tolerance towards various functional groups.
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