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A COMPARISON OF THE INFLUENCE OF TOLBUTAMIDE AND SMALL DOSES OF INSULIN ON THE SPLANCHNIC OUTPUT AND PERIPHERAL UPTAKE OF GLUCOSE IN MAN

1959; Wiley; Volume: 74; Issue: 3 Linguagem: Inglês

10.1111/j.1749-6632.1959.tb39578.x

1749-6632

James W. Craig, William R. Drucker, Max Miller, Hiram Woodward, Valerie J Molzahn,

Natural Products and Biological Research

Annals of the New York Academy of SciencesVolume 74, Issue 3 p. 537-547 A COMPARISON OF THE INFLUENCE OF TOLBUTAMIDE AND SMALL DOSES OF INSULIN ON THE SPLANCHNIC OUTPUT AND PERIPHERAL UPTAKE OF GLUCOSE IN MAN James W. Craig, James W. Craig The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this authorWilliam R. Drucker, William R. Drucker The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, Ohio Markle Scholar in The Medical Sciences.Search for more papers by this authorMax Miller, Max Miller The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this authorHiram Woodward Jr., Hiram Woodward Jr. The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this authorValerie Molzahn, Valerie Molzahn The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this author James W. Craig, James W. Craig The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this authorWilliam R. Drucker, William R. Drucker The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, Ohio Markle Scholar in The Medical Sciences.Search for more papers by this authorMax Miller, Max Miller The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this authorHiram Woodward Jr., Hiram Woodward Jr. The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this authorValerie Molzahn, Valerie Molzahn The Departments of Medicine and Surgery, The School of Medicine, Western Reserve University, The University Hospitals of Cleveland and Highland View, The Cuyahoga County Hospital, Cleveland, OhioSearch for more papers by this author First published: March 1959 https://doi.org/10.1111/j.1749-6632.1959.tb39578.xCitations: 12 The work reported in this paper was supported in part by the Diabetes Research Program of Western Reserve University, through Research Grant A-1317 from the National Institute of Arthritis and Metabolic Diseases, Public Health Service, Bethesda, Md., and the Fund for the Study of Diabetes Mellitus and Related Metabolic Diseases at Western Reserve University. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Loubatières, A. 1957. The mechanism of action of the hypoglycemic sulfonamides. A concept based on investigations in animals and in man. Diabetes. 6: 408–417. 2 Mirsky, I. A., G. Perisutti & S. Gitelson. 1957. The role of insulinase in the hypoglycemic response to sulfonylureas. Ann. N. Y. Acad. Sci. 71(1): 103–111. 3 Pozza, G., G. Galansino & P. P. Foà. 1956. Insulin secretion following carbutamide injections in normal dogs. Proc. Soc. Exptl. Biol. 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The physiologic significance of the secretion of endogenous insulin into the portal circulation. I. Comparison of the effects of glucagon-free insulin administered via the portal vein and via a peripheral vein on the magnitude of hypoglycemia and peripheral glucose utilization. J. Clin. Invest. 37: 631–639. 29 Moloney, P. J. & M. Coval. 1955. Antigenicity of insulin: diabetes induced by specific antibodies. Biochem. J. 59: 179–185. 30 Brown, H., F. Sanger & R. Kitai. 1955. The structure of pig and sheep insulins. Biochem. J. 60: 556–565. 31 Shreeve, W. W., N. Baker, M. Miller, R. A. Shipley, G. E. Incefy & J. W. Craig. 1956. C14 studies in carbohydrate metabolism. II. The oxidation of glucose in diabetic human subjects. Metabolism. 5: 22–34. Citing Literature Volume74, Issue3Chlorpropamide and Diabetes MellitusMarch 1959Pages 537-547 ReferencesRelatedInformation