Revisão Revisado por pares

Biosynthesis, Maturation, Release, and Degradation of Neurotensin and Neuromedin N

1992; Wiley; Volume: 668; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1992.tb27337.x

ISSN

1749-6632

Autores

Patrick Kitabgi, F. De Nadai, Carole Rovère, Jean-Noël Bidard,

Tópico(s)

Pharmacological Effects and Assays

Resumo

Annals of the New York Academy of SciencesVolume 668, Issue 1 p. 30-42 Biosynthesis, Maturation, Release, and Degradation of Neurotensin and Neuromedin N PATRICK KITABGI, Corresponding Author PATRICK KITABGI Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceAddress for correspondence: Patrick Kitabgi, Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 660 Route des Lucioles, 06560 Valbonne, France.Search for more papers by this authorFRANÇOIS DE NADAI, FRANÇOIS DE NADAI Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceSearch for more papers by this authorCAROLE ROVÈRE, CAROLE ROVÈRE Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceSearch for more papers by this authorJEAN-NOËL BIDARD, JEAN-NOËL BIDARD Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceSearch for more papers by this author PATRICK KITABGI, Corresponding Author PATRICK KITABGI Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceAddress for correspondence: Patrick Kitabgi, Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 660 Route des Lucioles, 06560 Valbonne, France.Search for more papers by this authorFRANÇOIS DE NADAI, FRANÇOIS DE NADAI Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceSearch for more papers by this authorCAROLE ROVÈRE, CAROLE ROVÈRE Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceSearch for more papers by this authorJEAN-NOËL BIDARD, JEAN-NOËL BIDARD Institut de Pharmacologie Moléculaire et Cellulaire du CNRS, Université de Nice-Sophia Antipolis, 06560 Valbonne, FranceSearch for more papers by this author First published: October 1992 https://doi.org/10.1111/j.1749-6632.1992.tb27337.xCitations: 62AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Dobner, P. R., D. L. Barber, L. Villa-Komaroff & C. McKiernan. 1987. Cloning and sequencing of cDNA for the canine neurotensin/neuromedin N precursor. Proc. Natl. Acad. Sci. USA 84: 3516–3520. 2 Minamino, N., K. Kangawa & H. Matsuo. 1984. Neuromedin N: A novel neurotensin-like peptide identified in porcine spinal cord. Biochem. Biophys. Res. Commun. 122: 542–549. 3 De Nadai, F., J. C. Cuber & P. Kitabgi. 1989. The characterization and regional distribution of neuromedin N-like immunoreactivity in rat brain using a highly sensitive and specific radioimmunoassay. Comparison with the distribution of neurotensin. Brain Res. 500: 193–198. 4 Cuber, J. C., C. Herrmann, P. Kitabgi, A. Bosshard, C. Bernard, F. de Nadai & J. A. Chayvialle. 1990. Neuromedin N is not released with neurotensin from rat ileum. Endocrinology 126: 1584–1592. 5 Kitabgi, P., Y. Masuo, A. Nicot, A. Bérod, J. C. Cuber & W. 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The purification and specificity of a neutral endopeptidase from rabbit kidney brush border. Biochem. J. 137: 477–488. 15 Schwartz, J. C., B. Malfroy & S. de la Baume. 1981. Biological inactivation of enkephalins and the role of enkephalin-dipeptidyl-carboxypeptidase ("enkephalinase") as neuropeptidase. Life Sci. 29: 1715–1740. 16 Orlowski, M., C. Michaud & T. G. Chu. 1983. A soluble metalloendopeptidase from rat brain. Purification of the enzyme and determination of specificity with synthetic and natural peptides. Eur. J. Biochem. 135: 81–88. 17 Checler, F., J. P. Vincent & P. Kitabgi. 1986. Purification and characterization of a novel neurotensin-degrading peptidase from rat brain synaptic membranes. J. Biol. Chem. 261: 11274–11281. 18 Checler, F., S. Amar, P. Kitabgi & J. P. Vincent. 1986. Catabolism of neurotensin by neural (neuroblastoma clone N1E115) and extraneural (HT29) cell lines. Peptides 7: 1071–1077. 19 Checler, F., J. Mazella, P. Kitabgi & J. P. Vincent. 1986. 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Brain Res. 398: 386–389. 24 Coquerel, A., I. Dubuc, P. Kitabgi & J. Costentin. 1988. Potentiation by thiorphan and bestatin of the naloxone-insensitive analgesic effects of neurotensin and neuromedin N. Neurochem. Int. 12: 361–366. 25 Dubuc, I., D. Nouel, A. Coquerel, J. F. Menard, P. Kitabgi & J. Costentin. 1988. Hypothermic effect of neuromedin N in mice and its potentiation by peptidase inhibitors. Eur. J. Pharmacol. 151: 117–121. 26 Zeytinoglu, F. N., P. Brazeau & C. Mougin. 1983. Regulation of neurotensin secretion in a mammalian C cell line: Effect of dexamethasone. Reg. Peptides 6: 147–154. 27 Wilkinson, J. M. 1986. Fragmentation of polypeptides of enzymic methods. In Practical Protein Chemistry–A Handbook. A. Darbre, Ed.: 121–148. John Wiley & Sons, Ltd. Chichester , England . 28 Kislauskis, E., B. Bullock, D. McNeil & P. R. Dobner. 1988. The rat gene encoding neurotensin and neuromedin N: Structure, tissue-specific expression, and evaluation of exon sequences. J. Biol. Chem. 263: 4963–4968. 29 Checler, F., P. Dauch, Y. Masuo & J. P. Vincent. 1991. Neurotensin and neuromedin N are differently metabolized in ventral tegmental area and nucleus accumbens. J. Neurochem. 56: 1320–1328. Citing Literature Volume668, Issue1The Neurobiology of NeurotensinOctober 1992Pages 30-42 ReferencesRelatedInformation

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