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Comportamento biológico de Leishmania (L.) amazonensis isolada de um gato doméstico (Felis catus) de Mato Grosso do Sul, Brasil

2010; UNIVERSIDADE FEDERAL DE GOIÁS; Volume: 39; Issue: 1 Linguagem: Inglês

10.5216/rpt.v39i1.9496

1980-8178

Isabele Dos Reis Martins Duarte, Carla Cardozo Pinto de Arruda, Ana Rachel Oliveira de Andrade, Vânia Lúcia Brandão Nunes, Alda Izabel de Souza, Doroty Mesquita Dourado, Sylvio Celso Gonçalves da Costa,

Trypanosoma species research and implications

Even though the main mammalian reservoirs of Leishmania described in theAmericas are rodents, opossums, horses, canines, and primates, the role of the catas a host of Leishmania has also been discussed. This work was performed in orderto study the histopathology of cutaneous lesions of mice infected with Leishmania(L.) amazonensis isolated from a cat in Ribas do Rio Pardo, Mato Grosso do Sul,Brazil. The histopathological analysis comprised an assessment of the intensityand composition of the inflammatory infiltrate, as well as parasite load. Miceexhibited a high degree of cutaneous parasitism in the paw, at 20 days post infection, demonstrating the high and rapid infectivity of the sample isolated from the cat. An intense and diffuse lymphohistiocytic, eosinophilic inflammatory infiltrate anda diffuse, moderate necrosis were observed at the site of infection. It is importantto note that the original cat presented no sign of immunosuppressive disease. Theoccurrence of visceralization was not observed, since no parasites were found in theliver or spleen 60 days after infection. Nonetheless, the liver presented focal andperivascular inflammatory reactions.