Artigo Revisado por pares

γ-Lactam analogues of monocyclic β-lactam antibiotics

1987; Elsevier BV; Volume: 28; Issue: 25 Linguagem: Inglês

10.1016/s0040-4039(00)96234-8

ISSN

1873-3581

Autores

Maxwell J. Crossley, Robyn L. Crumbie, Yik M. Fung, Jeffrey J. Potter, M. Pegler,

Tópico(s)

Antibiotic Resistance in Bacteria

Resumo

γ-Lactam analogues of monocyclic β-lactam antibiotics, the oxamazins, have been prepared from N-protected γ-nitro-α-amino acid esters. Unlike the oxamazins, these higher homologues are devoid of biological activity.

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