Cloning and sequencing of a gene encoding a new member of the tetratricopeptide protein family from magnetosomes of Magnetospirillum magnetotacticum
1996; Elsevier BV; Volume: 171; Issue: 1 Linguagem: Inglês
10.1016/0378-1119(95)00008-9
ISSN1879-0038
AutoresYoshihiro Okuda, Kimitoshi Denda, Yoshihiro Fukumori,
Tópico(s)Geology and Paleoclimatology Research
ResumoA gene encoding the 22-kDa protein (MAM22) which was localized in the magnetosomes isolated from the magnetotactic bacterium, Magnetospirillum magnetotacticum, was cloned and sequenced. MAM22 was composed of 220 amino acids (aa) with a molecular weight of 24 186 Da. The deduced aa sequence exhibited significant homology with a number of proteins that belong to the tetratricopeptide repeat (TPR) protein family, including mitochondrial protein import receptors and peroxisomal protein import receptors. The presence of three repeats of a degenerate 34-aa consensus sequence, suggest that MAM22 localized in magnetosome membranes may interact with the cytoplasmic proteins containing similar TPR motifs.
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