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Chronic studies in rats exposed to liquid effluent from coal gasification process

1981; Wiley; Volume: 1; Issue: 1 Linguagem: Inglês

10.1002/jat.2550010103

1099-1263

Krista Kostial, Maja Blanuša, I. Rabar, Tea Maljković, D. Kello, M. Landeka, A Bunarević, Jerry F. Stara,

Heavy metals in environment

Abstract The health effects of the E‐effluent (water for quenching ash) from a coal gasification plant were assayed in a chronic experiment (16 month exposure) and a three generation reproduction study. Animals exposed to 100% E‐effluent had an increased daily intake of various inorganic elements (Fe, Cu, K, I, Se, Cd, Hg, Pb, As, F and Cr). In spite of that, the exposed and control animals had the same mortality rate, haematological findings, urinary protein excretion, trace element concentrations in kidneys, liver and femur, bone composition and morphometry, and histological findings. The pre‐ and post‐natal development and growth was unchanged during three generations. It is concluded that the higher intake of various inorganics caused no change in the parameters measured.