Structures of merrilactones B and C, novel anislactone-type sesquiterpenes from Illicium merrillianum, and chemical conversion of anislactone B to merrilactone A
2001; Elsevier BV; Volume: 57; Issue: 22 Linguagem: Inglês
10.1016/s0040-4020(01)00418-5
ISSN1464-5416
AutoresJianmei Huang, Chunshu Yang, Masami Tanaka, Yoshiyasu Fukuyama,
Tópico(s)Pharmacological Effects of Natural Compounds
ResumoTwo new anislactone-type sesquiterpenes, merrilactones B (1) and C (2) were isolated from the pericarps of Illicium merrillianum along with anislactones A (4) and B (5). Their structures were elucidated by spectroscopic methods and chemical transformation and the structure of merrilactone C was established by X-ray crystallographic analysis of its methyl derivative. Merrilactone A (3), a unique anislactone-type sesquiterpene showing neurite outgrowth promoting activity, was effectively synthesized from anislactone B.
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