Biosynthesis and Mass Spectrometric Imaging of Tolaasin, the Virulence Factor of Brown Blotch Mushroom Disease
2013; Wiley; Volume: 14; Issue: 18 Linguagem: Inglês
10.1002/cbic.201300553
ISSN1439-7633
AutoresKirstin Scherlach, Gerald Lackner, Katharina Graupner, Sacha J. Pidot, Tom Bretschneider, Christian Hertweck,
Tópico(s)Silymarin and Mushroom Poisoning
ResumoKilling them softly. The molecular basis for the biosynthesis of tolaasin, the Pseudomonas tolaasii-derived causative agent of mushroom (Agaricus bisporus) soft rot, was revealed by genome mining and analysis of the NRPS genes. Production of the toxic lipopeptides during infection was confirmed by imaging mass spectrometry. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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