Artigo Acesso aberto Revisado por pares

Extractives of Australian Timbers. III. Afromosin (Castanin, 6,4'-Dimethoxy-7-hydroxyisoflavone) from Castanospermum australe Cunn. et Fras

1963; CSIRO Publishing; Volume: 16; Issue: 1 Linguagem: Inglês

10.1071/ch9630188

ISSN

1445-0038

Autores

RA Eade, H Hinterberger, JJH Simes,

Tópico(s)

Natural Products and Biological Research

Resumo

An examination of the triterpenoid extractives of Castanospermum australe Cunn.et Fras.has been reported by Simes (1950).Investigation of the phenolic constituents of the extract has led to the isolation of a new isoflavone, castanin, which was shown to be 6,4'-dimethoxy-7-hydroxyisoflavone (Hinterberger 1956).The structure of castanin has been briefly recorded by one of us (Simes et al. 1959); more recently McMurry and Theng (1960) have assigned the same structure to afromosin which was isolated from the wood of Afromosia elata Harms.Because of the detailed published work on afromosin, which is similar to our own studies, we now report those experiments not previously recorded.The melting points of afromosin and several of its derivatives as determined by us differ somewhat from those claimed by McMurry and Theng.Formononetin (7-hydroxy-4'-methoxyisoflavone) was also present in the phenolic fraction of the extract.

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