Portal de Periódicos da CAPES

Total Synthesis of (±)-Stemonamide and (±)-Isostemonamide Using a Radical Cascade

2007; American Chemical Society; Volume: 10; Issue: 2 Linguagem: Inglês

10.1021/ol702563p

1523-7060

Tsuyoshi Taniguchi, Genzo Tanabe, Osamu Muraoka, Hiroyuki Ishibashi,

Asymmetric Hydrogenation and Catalysis

Total synthesis of stemonamide and isostemonamide is described. The concise construction of the tricyclic core of these alkaloids was achieved by radical cascade involving 7-endo and 5-endo cyclizations.