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Glycosylated haemoglobin and red blood cells in diabetes

1980; Springer Science+Business Media; Volume: 19; Issue: 5 Linguagem: Inglês

10.1007/bf00281834

1432-0428

Arye Lev-Ran,

Neurological and metabolic disorders

Glycosylated haemoglobin has an increased affinity for oxygen [1], and in diabetics the number of red blood cells has been found to correlate with glycohaemoglobin (GHb) level [2]. If confirmed, this could indicate compensatory polycythaemia resulting from chronic hypoxaemia. We have reviewed in this respect our data relating to 79 adult diabetic males and 48 postmenopausal women, all of them living in the coastal area, non-smokers and suffering from no known heart, lung or blood diseases. No differences were found between patients treated by diet alone, oral drugs or insulin. Blood count was done in the Coulter counter, and GHb was determined by the Biorex 70 column method [3]. Results are presented in the table and show statistically significant but very weak correlation for GHb positively with of red blood cells (p = 0.04), and negatively with mean corpuscular volume (p = 0.034) in males only. Table. Red blood cells (RBC), haematocrit, mean corpuscular volume (MCV), and glycohaemoglobin (GHb) in diabetics (M + SD) Males Females