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Patients with Acinetobacter baumannii bloodstream infections are colonized in the gastrointestinal tract with identical strains

2010; Elsevier BV; Volume: 38; Issue: 9 Linguagem: Inglês

10.1016/j.ajic.2010.03.005

1527-3296

Kerri A. Thom, William Hsiao, Anthony D. Harris, O. Colin Stine, David A. Rasko, J. Kristie Johnson,

Urinary Tract Infections Management

In this study, we identified critically ill patients with Acinetobacter baumannii bacteremia and examined perirectal surveillance cultures for the presence of genetically related A baumannii strains using pulsed-field gel electrophoresis to determine whether gut colonization preceded clinical infection. Seven patients with imipenem-resistant A baumannii bacteremia were identified from January to June of 2008. Six of 7 (86%) patients were colonized in the gastrointestinal tract with genetically similar strains preceding their bacteremia. In this study, we identified critically ill patients with Acinetobacter baumannii bacteremia and examined perirectal surveillance cultures for the presence of genetically related A baumannii strains using pulsed-field gel electrophoresis to determine whether gut colonization preceded clinical infection. Seven patients with imipenem-resistant A baumannii bacteremia were identified from January to June of 2008. Six of 7 (86%) patients were colonized in the gastrointestinal tract with genetically similar strains preceding their bacteremia.