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Prenatal diagnosis of thalassaemia by haemoglobin chromatography on biorex an evaluation of the method

1984; Wiley; Volume: 4; Issue: 1 Linguagem: Inglês

10.1002/pd.1970040103

1097-0223

Sumitra Dash, John Panourgias, Photini Karababa, Dimitris Loukopoulos,

Neonatal Health and Biochemistry

Abstract The applicability of the chromatographic separation of haemoglobins F, A and S on Biorex 70 (Blouquit et al. , 1982) for the prenatal diagnosis of thalassaemia and related conditions was evaluated in comparison to the conventional globin chain separation technique. The method proved reliable, inexpensive and rapid and should be considered as a valuable alternative in laboratories carrying out great numbers of tests and those being newly set up for this purpose.