Artigo Acesso aberto Revisado por pares

Respiratory Variations in Pulse Oximetry Plethysmographic Waveform Amplitude to Predict Fluid Responsiveness in the Operating Room

2007; Lippincott Williams & Wilkins; Volume: 106; Issue: 6 Linguagem: Inglês

10.1097/01.anes.0000267593.72744.20

ISSN

1528-1175

Autores

Maxime Cannesson, Y. Attof, P. Rosamel, Olivier Desebbe, Pierre Joseph, Olivier Metton, Olivier Bastien, Jean-Jacques Lehot,

Tópico(s)

Blood Pressure and Hypertension Studies

Resumo

Respiratory variations in pulse oximetry plethysmographic waveform amplitude (DeltaPOP) are related to respiratory variations in pulse pressure (DeltaPP) and are sensitive to changes in preload. The authors hypothesized that DeltaPOP can predict fluid responsiveness in mechanically ventilated patients during general anesthesia.Twenty-five patients referred for cardiac surgery were studied after induction of general anesthesia. Hemodynamic data (cardiac index, central venous pressure, pulmonary capillary wedge pressure, DeltaPP, and DeltaPOP) were recorded before and after volume expansion (500 ml hetastarch, 6%). Fluid responsiveness was defined as an increase in cardiac index of 15% or greater.Volume expansion induced changes in cardiac index (2.0+/-0.4 to 2.3+/-0.5 mmHg; P<0.05), DeltaPP (11+/-7 to 6+/-5%; P<0.05), and DeltaPOP (12+/-9 to 7+/-5%; P<0.05). DeltaPOP and DeltaPP were higher in responders than in nonresponders (17+/-8 vs. 6+/-4 and 14+/-7 vs. 6+/-4%, respectively; P<0.05 for both). A DeltaPOP greater than 13% before volume expansion allowed discrimination between responders and nonresponders with 80% sensitivity and 90% specificity. There was a significant relation between DeltaPOP before volume expansion and percent change in cardiac index after volume expansion (r=0.62; P<0.05).DeltaPOP can predict fluid responsiveness noninvasively in mechanically ventilated patients during general anesthesia. This index has potential clinical applications.

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