Portal de Periódicos da CAPES

Aseptic loosening, not only a question of wear: A review of different theories

2006; Taylor & Francis; Volume: 77; Issue: 2 Linguagem: Inglês

10.1080/17453670610045902

1745-3682

Mikael Sundfeldt, Lars Carlsson, Carina B. Johansson, Peter Thomsen, Christina Gretzer,

Total Knee Arthroplasty Outcomes

Today, aseptic loosening is the most common cause of revision of major arthroplasties. Aseptic loosening accounts for more than two-thirds of hip revisions and almost one-half of knee revisions in Sweden. Several theories on the cause of aseptic loosening have been proposed. Most of these theories, however, are based on empiric observations, experimental animal models or anecdotal cases. In this review, we discuss the most common theories concerning aseptic loosening. It emerges from this review that aseptic loosening has a multifactorial etiology and cannot be explained by a single theory.