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Quinina: 470 anos de história, controvérsias e desenvolvimento

2009; Brazilian Chemical Society; Volume: 32; Issue: 7 Linguagem: Inglês

10.1590/s0100-40422009000700048

1678-7064

Alfredo R. M. Oliveira, Daiane Szczerbowski,

Science and Education Research

SCIENCE DEVELOPMENT.After 470 years, a history of development, international seed smuggling and scientific development that caused deep changes in our society, has reached an end.In 1638, the countess of Chinchón contracted a disease while in the Amazon rain forest and was healed by a potion used by the native inhabitants.In 1856, William H. Perkin while attempting to obtain synthetic quinine, discovered the mauveína, a molecule that changed the world.The synthesis of quinine was also the subject of a bitter controversy among two excellent scientists of the 20 th century.During centuries, quinine was the only hope against malaria disease and its exploration almost extinguished the Cinchona tree.