A New Antibiotic Nortriterpene Quinone Methide from Maytenus catingarum
1999; American Chemical Society; Volume: 62; Issue: 5 Linguagem: Inglês
10.1021/np980359p
ISSN1520-6025
AutoresNelson Alvarenga, Carlos Velázquez, Rafael José Vivero, Nancy J. Canela, Isabel L. Bazzocchi, Esteban Ferro,
Tópico(s)Bioactive Compounds and Antitumor Agents
Resumo15α-Hydroxy-21-keto-pristimerine (1), a new nortriterpene quinone methide was isolated from the root bark of Maytenus catingarum along with other well-known related compounds, including pristimerine (2), tingenone, and 20α-hydroxy-tingenone. The structure of 1 was determined by means of 1H and 13C NMR spectroscopy, including homonuclear and heteronuclear correlations. Compound 1 showed antibiotic activity against Gram-positive bacteria.
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