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Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

2015; Nature Portfolio; Volume: 47; Issue: 3 Linguagem: Inglês

10.1038/ng.3202

1546-1718

Adam Shlien, Brittany Campbell, Richard de Borja, Ludmil B. Alexandrov, Daniele Merico, David C. Wedge, Peter Van Loo, Patrick Tarpey, Paul Coupland, Sam Behjati, Aaron Pollett, Tatiana Lipman, Abolfazl Heidari, Shriya Deshmukh, N. Avitzur, Bettina Meier, Moritz Gerstung, Ye Hong, Diana M. Merino, Manasa Ramakrishna, Marc Remke, Roland Arnold, Gagan B. Panigrahi, Neha Thakkar, Karl P. Hodel, Erin E. Henninger, A. Yasemin Göksenin, Doua Bakry, George S. Charames, Harriet Druker, Jordan Lerner‐Ellis, Matthew Mistry, Rina Dvir, Ronald Grant, Ronit Elhasid, Roula Farah, Glenn Taylor, Paul C. Nathan, Sarah Alexander, Shay Ben‐Shachar, Simon C. Ling, Steven Gallinger, Shlomi Constantini, Peter B. Dirks, Annie Huang, Stephen W. Scherer, Richard G. Grundy, Carol Durno, Melyssa Aronson, Anton Gartner, M. Stephen Meyn, Michael D. Taylor, Zachary F. Pursell, Christopher E. Pearson, David Malkin, P. Andrew Futreal, Michael R. Stratton, Éric Bouffet, Cynthia Hawkins, Peter J. Campbell, Uri Tabori,

DNA Repair Mechanisms