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The synthesis of thieno[3,4-]furan using a tandem intramolecular-reverse Diels-Alder reaction approach

1986; Elsevier BV; Volume: 27; Issue: 26 Linguagem: Inglês

10.1016/s0040-4039(00)84712-7

1873-3581

J. MOURSOUNIDIS, Dieter Wege,

Synthesis and biological activity

The title compound has been prepared by a route involving as the key steps the intramolecular Diels-Alder addition between a furan and a pendant acetylenic ester, and the subsequent retro-Diels-Alder fragmentation of the adduct, induced by 3,6-di(pyridin-2′-yl)-s-tetrazine.