α‐actinin revisited: A fresh look at an old player
2004; Wiley; Volume: 58; Issue: 2 Linguagem: Inglês
10.1002/cm.20007
ISSN1097-0169
Autores Tópico(s)Caveolin-1 and cellular processes
ResumoCell MotilityVolume 58, Issue 2 p. 104-111 ViewFree Access α-actinin revisited: A fresh look at an old player Carol A. Otey, Corresponding Author Carol A. Otey [email protected] Department of Cell and Molecular Physiology, University of North Carolina, Chapel HillDepartment of Cell and Molecular Physiology, University of North Carolina, Chapel Hill, NC 27599-7545Search for more papers by this authorOlli Carpen, Olli Carpen Department of Anatomy and Neuroscience Program, Biomedicum, University of Helsinki, Helsinki, Finland Department of Pathology, Helsinki University Hospital, Helsinki, FinlandSearch for more papers by this author Carol A. Otey, Corresponding Author Carol A. Otey [email protected] Department of Cell and Molecular Physiology, University of North Carolina, Chapel HillDepartment of Cell and Molecular Physiology, University of North Carolina, Chapel Hill, NC 27599-7545Search for more papers by this authorOlli Carpen, Olli Carpen Department of Anatomy and Neuroscience Program, Biomedicum, University of Helsinki, Helsinki, Finland Department of Pathology, Helsinki University Hospital, Helsinki, FinlandSearch for more papers by this author First published: 05 April 2004 https://doi.org/10.1002/cm.20007Citations: 323AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES Apperson ML, Moon IS, Kennedy MB. 1996. Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family. J Neurosci 16: 6839– 6852. Araki N, Hatae T, Yamada T, Hirohashi S. 2000. Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging. J Cell Sci 113: 3329– 3340. Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, Takeuchi M, Takai Y. 2003. ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions. J Biol Chem 278: 4103– 4111. Bang ML, Mudry RE, McElhinny AS, Trombitas K, Geach AJ, Yamasaki R, Sorimachi H, Granzier H, Gregorio CC, Labeit S. 2001. Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies. J Cell Biol 153: 413– 427 Bauer K, Kratzer M, Otte M, de Quintana KL, Hagmann J, Arnold GJ, Eckerskorn C, Lottspeich F, Siess W. 2000. Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells. Blood 96: 4236– 4245. Beckerle MC. 1997. Zyxin: zinc fingers at sites of cell adhesion. Bioessays 19: 949– 957. Belkin AM, Koteliansky VE. 1987. Interaction of iodinated vinculin, metavinculin and alpha-actinin with cytoskeletal proteins. FEBS Lett 220: 291– 294. Bhatt A, Kaverina I, Otey C, Huttenlocher A. 2002. Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain. J Cell Sci 115: 3415– 3425. Boukhelifa M, Parast MM, Valtschanoff JG, LaMantia AS, Meeker RB, Otey CA. 2001. A role for the cytoskeleton-associated protein palladin in neurite outgrowth. Mol Biol Cell 12: 2721– 2729. Boukhelifa M, Hwang SJ, Valtschanoff JG, Meeker RB, Rustioni A, Otey CA. 2003. A critical role for palladin in astrocyte morphology and response to injury. Mol Cell Neurosci 23: 661– 668. Broderick MJF, Winder SJ. 2002. Towards a complete atomic structure of spectrin family proteins. J Struct Biol 137: 184– 193. Burgueño J, Blake DJ, Benson MA, Tinsley CL, Esapa CT, Canela EI, Penela P, Mallol J, Mayor F Jr, Lluis C, Franco R, Ciruela F. 2003. The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin. J Biol Chem 278: 37545– 37552. Burridge K, Feramisco, JR. 1981. Non-muscle α-actinins are calcium sensitive actin binding proteins. Nature 294: 565– 567. Cao Y, Kang Q, Zolkiewska A. 2001. Metalloprotease-disintegrin ADAM 12 interacts with alpha-actinin-1. Biochem J 357: 353– 361. Carpen O, Pallai P, Staunton DE, Springer TA. 1992. Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin. J Cell Biol 118: 1223– 1234. Christerson LB, Vanderbilt CA, Cobb MH. 1999. MEKK1 interacts with alpha-actinin and localizes to stress fibers and focal adhesions. Cell Motil Cytoskeleton 43: 186– 198. Crawford AW, Michelsen JW, Beckerle MC. 1992. An interaction between zyxin and alpha-actinin. J Cell Biol 116: 1381– 1393. Cuevas BD, Abell AN, Witowsky JA, Yujiri T, Johnson NL, Kesavan K, Ware M, Jones PL, Weed SA, DeBiasi RL, Oka Y, Tyler KL, Johnson GL. 2003. MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts. EMBO J 22: 3346– 3355. Daniliuc S, Bitterman H, Rahat MA, Kinarty A, Rosenzweig D, Nitza L. 2003. Hypoxia inactivates inducible nitric oxide synthase in mouse macrophages by disrupting its interaction with alpha-actinin 4. J Immunol 171: 3225– 3232. Djinovic-Carugo K, Gautel M, Ylanne J, Young P. 2002. The spectrin repeat: a structural platform for cytoskeletal protein assemblies. FEBS Lett 513: 119– 123. Dourdin N, Bhatt AK, Dutt P, Greer PA, Arthur JS, Elce JS, Huttenlocher A. 2001. Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts. J Biol Chem 276: 48382– 48288. Drees BE, Andrews KM, Beckerle MC. 1999. Molecular dissection of zyxin function reveals its involvement in cell motility. J Cell Biol 147: 1549– 1560. Dwir O, Kansas GS, Alon R. 2001. Cytoplasmic anchorage of L-selectin controls leukocyte capture and rolling by increasing the mechanical stability of the selectin tether. J Cell Biol 155: 145– 156. Egerton M, Moritz RL, Druker B, Kelso A, Simpson RJ. 1996. Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. Biochem Biophys Res Commun 224: 666– 674. Feng S, Resendiz JC, Christodoulides N, Lu X, Arboleda D, Berndt MC, Kroll MH. 2002. Pathological shear stress stimulates the tyrosine phosphorylation of alpha-actinin associated with the glycoprotein Ib-IX complex. Biochemistry 41: 1100– 1108. Fraley TS, Tran TC, Corgan AM, Nash CA, Hao J, Critchley DR, Greenwood JA. 2003. Phosphoinositide binding inhibits alpha-actinin bundling activity. J Biol Chem 278: 24039– 24045. Gluck U, Ben-Ze'ev A. 1994. Modulation of alpha-actinin levels affects cell motility and confers tumorigenicity on 3T3 cells. J Cell Sci 107: 1773– 1782. Gonzalez AM, Otey C, Edlund M, Jones JC. 2001. Interactions of a hemidesmosome component and actinin family members. J Cell Sci 114: 4197– 4206. Greene DK, Tumova S, Couchman JR, Woods A. 2003. Syndecan-4 associates with alpha-actinin. J Biol Chem 278: 7617– 7623. Greenwood JA, Theibert AB, Prestwich GD, Murphy-Ullrich JE. 2000. Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin. J Cell Biol 150: 627– 642. Guvakova MA, Adams JC, Boettiger D. 2002. Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J Cell Sci 115: 4149– 4165. Hauser MA, Horrigan SK, Salmikangas P, Torian UM, Viles KD, Dancel R, Tim RW, Taivainen A, Bartoloni L, Gilchrist JM, Stajich JM, Gaskell PC, Gilbert JR, Vance JM, Pericak-Vance MA, Carpen O, Westbrook CA, Speer MC. 2000. Myotilin is mutated in limb girdle muscular dystrophy 1A. Hum Mol Genet 9: 2141– 2147. Heiska L, Kantor C, Parr T, Critchley DR, Vilja P, Gahmberg CG, Carpen O. 1996. Binding of the cytoplasmic domain of intercellular adhesion molecule-2 (ICAM-2) to alpha-actinin. J Biol Chem 271: 26214– 26219. Honda K, Yamada T, Endo R, Ino Y, Gotoh M, Tsuda H, Yamada Y, Chiba H, Hirohashi S. 1998. Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion. J Cell Biol 140: 1383– 1393. Izaguirre G, Aguirre L, Ji P, Aneskievich B, Haimovich B. 1999. Tyrosine phosphorylation of alpha-actinin in activated platelets. J Biol Chem 274: 37012– 37020. Izaguirre G, Aguirre L, Hu YP, Lee HY, Schlaepfer DD, Aneskievich BJ, Haimovich B. 2001. The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase. J Biol Chem 276: 28676– 28685. Kansas GS, Pavalko FM. 1996. The cytoplasmic domains of E- and P-selectin do not constitutively interact with alpha-actinin and are not essential for leukocyte adhesion. J Immunol 157: 321– 325. Kaplan JM, Kim SH, North KN, Rennke H, Correia LA, Tong HQ, Mathis BJ, Rodriguez-Perez JC, Allen PG, Beggs AH, Pollak MR. 2000. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis. Nat Genet 24: 251– 256. Kato M, Sasaki T, Ohya T, Nakanishi H, Nishioka H, Imamura M, Takai Y. 1996. Physical and functional interaction of rabphilin-3A with alpha-actinin. J Biol Chem 271: 31775– 31778. Kim JH, Lee-Kwon W, Park JB, Ryu SH, Yun CH, Donowitz M. 2002. Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis. J Biol Chem 277: 23714– 23724. Knudsen KA, Soler AP, Johnson KR, Wheelock MJ. 1995. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol 130: 67– 77. Kos CH, Le TC, Sinha S, Henderson JM, Kim SH, Sugimoto H, Kalluri R, Gerszten RE, Pollak MR. 2003. Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest 111: 1683– 1690. Krupp JJ, Vissel B, Thomas CG, Heinemann SF, Westbrook GL. 1999. Interactions of calmodulin and alpha-actinin with the NR1 subunit modulate Ca2+-dependent inactivation of NMDA receptors. J Neurosci 19: 1165– 1178 Lazarides E, Burridge K. 1975. Alpha-actinin: immunofluorescent localization of a muscle structural protein in nonmuscle cells. Cell 6: 289– 298. Merlot S, Firtel RA. 2003. Leading the way: directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J Cell Sci 116: 3471– 3478. Michaud JL, Lemieux LI, Dube M, Vanderhyden BC, Robertson SJ, Kennedy CR. 2003. Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4. J Am Soc Nephrol 14: 1200– 1211. Mukai H, Toshimori M, Shibata H, Takanaga H, Kitagawa M, Miyahara M, Shimakawa M, Ono Y. 1997. Interaction of PKN with alpha-actinin. J Biol Chem 272: 4740– 4746. Mykkänen OM, Gronholm M, Ronty M, Lalowski M, Salmikangas P, Suila H, Carpen O. 2001. Characterization of human palladin, a microfilament-associated protein. Mol Biol Cell 12: 3060– 3073. Nikolopoulos SN, Spengler BA, Kisselbach K, Evans AE, Biedler JL, Ross RA. 2000. The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells. Oncogene 19: 380– 386. Nix DA, Fradelizi J, Bockholt S, Menichi B, Louvard D, Friederich E, Beckerle MC. 2001. Targeting of zyxin to sites of actin membrane interaction and to the nucleus. J Biol Chem 276: 34759– 34767. Otey CA, Pavalko FM, Burridge K. 1990. An interaction between alpha-actinin and the beta 1 integrin subunit in vitro. J Cell Biol 111: 721– 729. Parast MM, Otey CA. 2000. Characterization of palladin, a novel protein localized to stress fibers and cell adhesions. J Cell Biol 150: 643– 656. Patrie KM, Drescher AJ, Welihinda A, Mundel P, Margolis B. 2002. Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1. J Biol Chem 277: 30183– 30190. Pavalko FM, Burridge K. 1991. Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin. J Cell Biol 114: 481– 491. Pavalko FM, LaRoche SM. 1993. Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin. J Immunol 151: 3795– 3807. Pavalko FM, Walker DM, Graham L, Goheen M, Doerschuk CM, Kansas GS. 1995. The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin. J Cell Biol 129: 1155– 1164. Pomies P, Louis HA, Beckerle MC. 1997. CRP1, a LIM domain protein implicated in muscle differentiation, interacts with alpha-actinin. J Cell Biol 139: 157– 168. Rajfur Z, Roy P, Otey C, Romer L, Jacobson K. 2002. Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins. Nat Cell Biol 4: 286– 293. Reinhard M, Zumbrunn J, Jaquemar D, Kuhn M, Walter U, Trueb B. 1999. An alpha-actinin binding site of zyxin is essential for subcellular zyxin localization and alpha-actinin recruitment. J Biol Chem 274: 13410– 13418. Resendiz JC, Feng S, Ji G, Kroll MH. 2004. von Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex. J Thromb Haemost 2: 161– 169. Salmikangas P, Mykkanen OM, Gronholm M, Heiska L, Kere J, Carpen O. 1999. Myotilin, a novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy. Hum Mol Genet 8: 1329– 1336. Shibasaki F, Fukami K, Fukui Y, Takenawa T. 1994. Phosphatidylinositol 3-kinase binds to alpha-actinin through the p85 subunit. Biochem J 302: 551– 557. Schultheiss T, Choi J, Lin ZX, DiLullo C, Cohen-Gould L, Fischman D, Holtzer H. 1992. A sarcomeric alpha-actinin truncated at the carboxyl end induces the breakdown of stress fibers in PtK2 cells and the formation of nemaline-like bodies and breakdown of myofibrils in myotubes. Proc Natl Acad Sci USA 89: 9282– 9286. Tang J, Taylor DW, Taylor KA. 2001. The three-dimensional structure of alpha-actinin obtained by cryoelectron microscopy suggests a model for Ca(2+)-dependent actin binding. J Mol Biol 310: 845– 858. Vallenius T, Makela TP. 2002. Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM. J Cell Sci 115: 2067– 2073. Vallenius T, Luukko K, Makela TP. 2000. CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4. J Biol Chem 275: 11100– 11105. Wachsstock DH, Wilkins JA, Lin S. 1987. Specific interaction of vinculin with alpha-actinin. Biochem Biophys Res Commun 146: 554– 560. Walikonis RS, Oguni A, Khorosheva EM, Jeng CJ, Asuncion FJ, Kennedy MB. 2001. Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin. J Neurosci 21: 423– 433. Wyszynski M, Lin J, Rao A, Nigh E, Beggs AH, Craig AM, Sheng M. 1997. Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Nature 385: 439– 442. Wyszynski M, Kharazia V, Shanghvi R, Rao A, Beggs AH, Craig AM, Weinberg R, Sheng M. 1998. Differential regional expression and ultrastructural localization of alpha-actinin-2, a putative NMDA receptor-anchoring protein, in rat brain. J Neurosci 18: 1383– 1392. Ylänne J, Scheffzek K, Young P, Saraste M. 2001. Crystal structure of the alpha-actinin rod reveals an extensive torsional twist. Structure (Camb) 9: 597– 604. Yujiri T, Ware M, Widmann C, Oyer R, Russell D, Chan E, Zaitsu Y, Clarke P, Tyler K, Oka Y, Fanger GR, Henson P, Johnson GL. 2000. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation. Proc Natl Acad Sci USA 97: 7272– 7277. Citing Literature Volume58, Issue2June 2004Pages 104-111 ReferencesRelatedInformation
Referência(s)