N,N-Dimethylchlorosulfitemethaniminium chloride (SOCl2-DMF) a versatile dehydrating reagent.
1984; Elsevier BV; Volume: 25; Issue: 31 Linguagem: Inglês
10.1016/s0040-4039(01)81386-1
ISSN1873-3581
AutoresAna Arrieta, J. M. Aizpurua, Claudio Palomo,
Tópico(s)Chemical Synthesis and Analysis
ResumoN,N-dimethylchlorosulfitemethaniminium chloride formed from thionyl chloride and dimethylformamide was found and efficient reagent for the synthesis of acyl azides from carboxylic acids and nitriles from oximes. It is also highly efficient for the direct synthesis of beta-lactams from carboxylic acids and imines avoiding the use of acid chlorides.
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