Tritiated Thymidine Uptake in Chondrocytes of Chickens Afflicted with Tibial Dyschondroplasia
1985; American Association of Avian Pathologists; Volume: 29; Issue: 4 Linguagem: Inglês
10.2307/1590476
ISSN1938-4351
AutoresCarol V. Gay, Roland M. Leach,
Tópico(s)Virus-based gene therapy research
Resumo3H-Thymidine was localized in sections of growth-plate cartilage and associated tibial dyschondroplastic lesion by autoradiography. One hour after 3H-thymidine was injected, radioactivity was found in the proliferating zone; after 48 hr it was also in the hypertrophic zone, and by 96 hr it was present in cells that were 4 to 5 mm into the lesion. This indicates that the lesion develops from the growth plate itself. The life span of the cells in the growth plate appears to be about 48 hr.
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