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Multiple sclerosis starting before the age of 18 years: the Brazilian experience

2013; Thieme Medical Publishers (Germany); Volume: 71; Issue: 10 Linguagem: Inglês

10.1590/0004-282x20130122

1678-4227

Yára Dadalti Fragoso, Maria Lúcia Brito Ferreira, Nívea de Macedo Oliveira Morales, Walter Oleschko Arruda, Joseph Bruno Bidin Brooks, Denise Sisterolli Diniz Carneiro, Margarete de Jesus Carvalho, Elizabeth Regina Comini-Frota, Éber Castro Corrêa, Carlos Augusto de Albuquerque Damasceno, Renán Barros Domingues, Alessandro Finkelsztejn, Paulo Diniz da Gama, Sidney Gomes, Marcus Vinícius Magno Gonçalves, Anderson Kuntz Grzesiuk, Jussara Mathias Netto Khouri, Damacio Ramón Kaimen-Maciel, María Fernanda Mendes, Rogério de Rizo Morales, Steve Biko Menezes Hora Alves Ribeiro, T.A.G.J. Ribeiro, Lívia Brito Bezerra de Albuquerque, Andrea Anacleto, Juliana Finkelsztejn, Rodrigo Assad Diniz da Gama, Josiane Lopes, Celso Luis Silva Oliveira, Francisco Tomaz Meneses de Oliveira, Leopoldo Antônio Pires, Patricia Correia de Oliveira Saldanha, Adélia Henriques Souza, Alex Eduardo da Silva,

Systemic Sclerosis and Related Diseases

Multiple sclerosis (MS) starting in childhood and adolescence poses a challenge for diagnosis and management of the disease. The aim of the present study was to assess the characteristics of early onset MS in Brazilian patients. Methods Retrospective data collection from specialized MS units. Results From 20 MS units in 11 Brazilian states, 117 cases of MS starting before the age of 18 years were collected. These patients had an average of 10 years of disease duration, still typically with low disability and one relapse every 2.5 years. The mean age for disease onset was 13.7 years. Conclusion The present study introduces a large series of Brazilian cases of pediatric MS. Although some patients presented a very severe form of MS, on the whole the group of patients with MS starting in childhood or adolescence presented a relatively mild form of this disease in Brazil.