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Ultrastructural and immunohistochemical study of the telencephalo-habenulo-interpeduncular connections of the goldfish

1994; Elsevier BV; Volume: 34; Issue: 1 Linguagem: Inglês

10.1016/0361-9230(94)90178-3

1873-2747

L. Villani, Lucia Dipietrangelo, C Pallotti, Paolo Pettazzoni, Isabella Zironi, Tiziana Guarnieri,

Ichthyology and Marine Biology

Surgical ablations of telencephalon or telencephalon plus habenular nuclei (HBN) have been performed for studying anatomical connections of the telencephalo-habenulo- interpeduncular system of the goldfish. The results of the ultrastructural studies confirmed the presence of massive telencephalo-habenular and habenulo-interpeduncular projections and, in addition, demonstrated a minor direct telencephalo-interpeduncular connection. Immunohistochemical localization of substance P in the interpeduncular nucleus (IPN) after telencephalic ablation failed to demonstrate the involvement of this neurotransmitter in the direct telencephalo-interpeduncular projection, while telencephalon plus HBN ablation reduced substance P immunoreactivity in the IPN. The different distribution of degenerating terminals converging on the IPN from the HBN and from the telencephalon suggested a subnuclear organization of this area, as described in mammals.