Two novel non-viral gene delivery vectors: low molecular weight polyethylenimine cross-linked by (2-hydroxypropyl)-β-cyclodextrin or (2-hydroxypropyl)-γ-cyclodextrin
2006; Royal Society of Chemistry; Issue: 22 Linguagem: Inglês
10.1039/b601130f
ISSN1364-548X
AutoresHongliang Huang, Guping Tang, Qingqing Wang, Da Li, Fen-ping Shen, Jun Zhou, Hai Yu,
Tópico(s)Viral Infectious Diseases and Gene Expression in Insects
ResumoTwo novel polymers of low molecular weight polyethylenimine cross-linked by (2-hydroxypropyl)-β-cyclodextrin or (2-hydroxypropyl)-γ-cyclodextrin showed lower cytotoxicity and higher transfection efficiency for the delivery of plasmid DNA compared with those of polyethylenimine (PEI, 25 kDa).
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